Ofloxacin Al

Ofloxacin, the active ingredient in Ofloxacin Al, is a fluoroquinolone presented as an oral dosage form for oral use. It treats bacterial infections such as urinary tract, respiratory, skin and gastrointestinal infections in adult patients.

GNH USA supplies Ofloxacin Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum antibacterial indicated for infections of several organ systems.

Urinary tract infections: eradicates common uropathogens and resolves symptoms. Respiratory tract infections: treats community‑acquired pneumonia and bronchitis caused by susceptible bacteria. Skin and soft tissue infections: clears cellulitis, abscesses and wound infections. Gastrointestinal infections: effective against bacterial dysentery and enteric pathogens.

Adverse reactions may occur with Ofloxacin use.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, often self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness. - Abdominal pain: cramping or discomfort. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles, may occur without warning. - QT interval prolongation: risk of cardiac arrhythmia. - Severe allergic reactions: anaphylaxis, angioedema. - Clostridioides difficile infection: severe colitis. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Peripheral neuropathy: sensory loss or tingling.

Before prescribing Ofloxacin, clinicians should consider patient‑specific factors.

Assess renal function: adjust dosing in impaired clearance. Monitor for tendon pain: discontinue if signs of tendinopathy appear. Avoid concurrent NSAIDs: increased risk of gastrointestinal bleeding. Use with caution in elderly: higher incidence of adverse events. Do not use in patients with known hypersensitivity to fluoroquinolones. Store at ambient temperature: keep in original container, protect from moisture.

Ofloxacin may interact with several medicines; awareness of interaction severity is essential.

Major Interactions (Avoid): - Tizanidine: may cause profound hypotension. - Warfarin: increased anticoagulant effect, risk of bleeding. - Theophylline: elevated plasma levels, potential toxicity. - Antacids containing magnesium or aluminum: reduce Ofloxacin absorption. - Cyclosporine: increased risk of nephrotoxicity.

Moderate Interactions (Monitor Closely): - Nonsteroidal anti‑inflammatory drugs: heightened gastrointestinal risk. - Corticosteroids: potential for tendon rupture. - Oral contraceptives: reduced efficacy, advise backup method. - Diabetic agents: possible alteration of glucose control. - Other fluoroquinolones: additive QT prolongation risk.