Oflaton (Ofloxacin)

Ofloxacin, the active ingredient in Oflaton, is a fluoroquinolone antibiotic presented as a strength/form for oral use. It treats a variety of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH USA supplies Oflaton as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ofloxacin is a broad‑spectrum antibacterial that acts on Gram‑negative and Gram‑positive organisms in several organ systems.

- Urinary tract infection: helps eradicate the causative bacteria and relieve symptoms. - Respiratory tract infection: aids in clearing bacterial pneumonia, bronchitis and sinusitis. - Skin and soft‑tissue infection: assists in eliminating pathogens causing cellulitis and wound infections. - Sexually transmitted infection: used as part of therapy for uncomplicated gonorrhoea. - Eye infection: formulated for ophthalmic use to treat bacterial conjunctivitis.

Ofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild stomach upset often reported. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient headache without neurological signs. - Dizziness: occasional light‑headedness. - Rash: mild skin erythema or itching. - Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially in the Achilles. - QT prolongation: irregular heart rhythm detectable on ECG. - Severe allergic reaction: anaphylaxis with swelling, breathing difficulty. - Peripheral neuropathy: numbness or tingling in extremities. - Clostridioides difficile infection: severe colitis with watery diarrhea.

When prescribing Ofloxacin, clinicians should evaluate patient history and monitor for specific risks.

- Renal impairment: adjust dose or avoid if severe kidney dysfunction. - Hepatic disease: use with caution in patients with liver impairment. - Pregnancy and lactation: avoid unless clearly needed, as fetal risk is not established. - Concomitant QT‑prolonging drugs: monitor cardiac rhythm. - History of tendon disorders: avoid in patients with prior tendon injury. - Store at below 25°C: keep in original container, protect from moisture and direct sunlight.

Ofloxacin can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Antacids containing aluminium or magnesium: reduce Ofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - NSAIDs (non‑steroidal anti‑inflammatory drugs): heightened risk of CNS stimulation.

Moderate Interactions (Monitor Closely): - CYP1A2 inhibitors (e.g., ciprofloxacin): may increase Ofloxacin plasma levels. - Diabetic agents (sulfonylureas): potential for hypoglycaemia. - Corticosteroids: increased risk of tendon rupture.