GNH USA

Europe — EMA

Odyral (Dorzolamide)

GNH USA supplies Odyral (Dorzolamide), a carbonic anhydrase inhibitor for open‑angle glaucoma and ocular hypertension. Request a quote for global supply.

Dorzolamide

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What is Dorzolamide?

Dorzolamide, the active ingredient in Odyral, is a carbonic anhydrase inhibitor presented as sterile ophthalmic eye drops for topical ocular use. It reduces aqueous humor production, thereby lowering intra‑ocular pressure in patients diagnosed with open‑angle glaucoma and ocular hypertension.

GNH USA supplies Odyral as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, and clinics across global markets while adhering to stringent quality and regulatory standards, and ensuring reliable delivery and post‑market support through its established distribution network.

What is Dorzolamide used for?

Odyral (dorzolamide) is used in the management of ocular conditions that involve elevated intra‑ocular pressure.

- Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression. - Ocular hypertension: lowers eye pressure to prevent development of glaucoma. - Secondary glaucoma: helps control pressure when caused by other ocular diseases or trauma.

What are the side effects of Dorzolamide?

Adverse reactions to dorzolamide eye drops may vary in frequency and severity.

Common Side Effects: - Burning or stinging sensation in the eye. - Temporary blurred vision. - Taste disturbance (metallic taste). - Redness of the conjunctiva.

Serious or Rare Side Effects: - Severe allergic reaction (angioedema, swelling of eyelids). - Persistent ocular pain. - Vision loss. - Stevens‑Johnson syndrome.

What precautions apply to Dorzolamide?

When using Odyral, follow these safety measures:

- Use only as prescribed: follow ophthalmologist instructions for dosing frequency. - Avoid contact with other eyes: do not share the bottle. - Monitor intra‑ocular pressure: regular check‑ups are required. - Discontinue if severe irritation occurs: seek medical advice promptly. - Store at room temperature: keep in original container, protect from light and moisture.

What does Dorzolamide interact with?

Dorzolamide may interact with other medications; consider the following:

Major Interactions (Avoid): - Systemic carbonic anhydrase inhibitors (e.g., acetazolamide): may increase risk of systemic side effects. - Topical ocular anesthetics: can enhance corneal toxicity.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation. - Beta‑blocker eye drops: additive intra‑ocular pressure lowering effect. - Anticholinergic agents: potential for reduced tear production.

Frequently asked questions

What is Odyral used for?+
Odyral contains dorzolamide, indicated for management of elevated intra‑ocular pressure in conditions such as open‑angle glaucoma and ocular hypertension. The medication is administered as topical eye drops and is part of a comprehensive glaucoma treatment regimen that may include other agents or laser therapy.
How does dorzolamide work?+
Dorzolamide inhibits carbonic anhydrase in the ciliary body, decreasing the production of aqueous humor. This reduction in fluid formation lowers intra‑ocular pressure, which helps to protect the optic nerve from pressure‑related damage in glaucoma and ocular hypertension.
What is the usual dose of Odyral?+
The dosing schedule for Odyral is determined by the prescribing ophthalmologist based on the patient’s condition, severity, and response to therapy. Typically, one drop is instilled in the affected eye(s) one to three times daily, but the exact regimen must be individualized.
Is Odyral safe during pregnancy or breastfeeding?+
Safety data for dorzolamide in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.
How do I order Odyral from GNH USA?+
To request Odyral, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Odyral compare with other glaucoma eye drops?+
Odyral (dorzolamide) belongs to the carbonic anhydrase inhibitor class, which lowers intra‑ocular pressure by reducing aqueous humor production. This mechanism differs from beta‑blockers that decrease fluid production via adrenergic blockade, and from prostaglandin analogues that increase outflow. Choice of therapy depends on efficacy, tolerability, patient comorbidities and physician preference.
How should Odyral be stored and handled?+
Store Odyral eye drops at room temperature, below 25 °C, in the original container. Keep the bottle tightly closed, protect it from light and moisture, and do not freeze. Do not use the product after the expiration date printed on the label.
How is Odyral administered?+
Odyral is applied as a sterile ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac of the affected eye(s). Close the eye gently and avoid blinking excessively for a few seconds to allow absorption.
What are the most serious risks associated with Odyral?+
Although uncommon, serious adverse reactions can include severe allergic responses such as angioedema or Stevens‑Johnson syndrome, persistent ocular pain, and sudden loss of vision. Patients should seek immediate medical attention if they experience swelling of the eyelids, rash, or any rapid deterioration in visual acuity.
Who should not use Odyral?+
Odyral is contraindicated in individuals with known hypersensitivity to dorzolamide, any carbonic anhydrase inhibitor, or any component of the formulation. It should also be avoided in patients with severe sulfonamide allergy, as cross‑reactivity may occur. Consultation with an eye care professional is essential before initiating therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Dorzolamide
Route
Ocular Use
Manufacturer
Orifarm Healthcare A/S
Origin
EU

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