Europe — EMA
Octreoscan (Indium In-111 Pentetreotide)
Indium In-111 pentetreotide, the active ingredient in Octreoscan, is a somatostatin analog presented as a radiopharmaceutical for intravenous use.
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What is Indium In-111 Pentetreotide?
Indium In-111 pentetreotide, the active ingredient in Octreoscan, is a somatostatin analog presented as a radiopharmaceutical for intravenous use. It is employed in diagnostic imaging to locate neuroendocrine tumours and assess somatostatin receptor expression in adult patients. GNH USA supplies Octreoscan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.
GNH USA supplies Octreoscan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.
What is Indium In-111 Pentetreotide used for?
Octreoscan is used in nuclear medicine to image neuro‑endocrine tumours that express somatostatin receptors.
- Gastroenteropancreatic neuroendocrine tumours: helps detect the extent of disease and guides therapeutic planning. - Carcinoid syndrome tumours: assists in localising tumour sites for surgical or medical management. - Metastatic neuroendocrine lesions: aids in staging and evaluating treatment response.
What are the side effects of Indium In-111 Pentetreotide?
Side effects are generally mild and related to the radiopharmaceutical nature of the preparation.
Common Side Effects: - Nausea - Transient flushing of the face - Mild abdominal pain - Localised injection site discomfort - Low‑grade headache - Temporary fatigue
Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Significant hypotension - Acute renal injury due to radiation exposure - Hematologic toxicity (e.g., thrombocytopen or leukocytopenia) - Persistent vomiting - Unusual skin rash or hives
What precautions apply to Indium In-111 Pentetreotide?
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