Europe — EMA
Octaplex
Human Coagulation Factor IX, the active ingredient in Octaplex, is a coagulation factor presented as a sterile injectable solution for intravenous use.
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What is Human Coagulation Factor Ix, Protein C, Human Coagulation Factor Vii, Protein S, Human Coagulation F?
Human Coagulation Factor IX, the active ingredient in Octaplex, is a coagulation factor presented as a sterile injectable solution for intravenous use. It is used to treat and prevent bleeding episodes in patients with hemophilia B and other inherited coagulation factor deficiencies. GNH USA supplies Octaplex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.
GNH USA supplies Octaplex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.
What is Human Coagulation Factor Ix, Protein C, Human Coagulation Factor Vii, Protein S, Human Coagulation F used for?
Octaplex is a plasma‑derived coagulation factor concentrate that acts on the intrinsic pathway of the clotting cascade.
- Hemophilia B: provides functional Factor IX to reduce bleeding frequency and severity. - Acquired Factor IX deficiency: replaces missing factor to control hemorrhage. - Peri‑operative management: supports hemostasis during surgery for patients with known factor deficiencies.
What are the side effects of Human Coagulation Factor Ix, Protein C, Human Coagulation Factor Vii, Protein S, Human Coagulation F?
Octaplex may cause adverse reactions ranging from mild to severe.
Common Side Effects: - Fever - Headache - Nausea - Mild infusion‑related erythema - Transient increase of ALT enzymes - Mild hypotension
Serious or Rare Side Effects: - Anaphylactic reaction - Thromboembolic events - Severe hypotension - Hemolysis - Development of inhibitors against Factor IX - Acute renal injury
What precautions apply to Human Coagulation Factor Ix, Protein C, Human Coagulation Factor Vii, Protein S, Human Coagulation F?
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