GNH USA

Europe — EMA

Nystatyna Teva (Nystatin)

GNH USA supplies Nystatyna Teva (Nystatin), a polyene antifungal for oral and esophageal candidiasis. Contact us for pricing and worldwide delivery.

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What is Nystatin?

Nystatin, the active ingredient in Nystatyna Teva, is a polyene antifungal presented as an oral dosage form for oral use. It treats Candida infections of the mouth and esophagus in patients with oral or esophageal candidiasis. GNH USA supplies Nystatyna Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Nystatin used for?

Nystatin is a polyene antifungal that acts on Candida species affecting the oral and upper gastrointestinal tract. - Oral candidiasis (thrush): reduces fungal load and relieves symptoms in patients with mouth Candida infection. - Esophageal candidiasis: clears Candida from the esophagus, improving swallowing and reducing pain. - Denture‑related stomatitis: eliminates Candida overgrowth on denture surfaces, helping resolve inflammation.

What are the side effects of Nystatin?

Nystatin may cause adverse reactions, most of which are mild and limited to the gastrointestinal tract or skin.

Common Side Effects: - Nausea: mild discomfort in the stomach after oral administration. - Vomiting: occasional expulsion of stomach contents. - Diarrhea: loose stools occurring during treatment. - Abdominal pain: cramping or discomfort in the abdomen. - Altered taste: temporary change in taste perception. - Mild rash: skin redness or itching at the site of contact.

Serious or Rare Side Effects: - Severe allergic reaction: anaphylaxis with difficulty breathing, swelling, or hives. - Hepatotoxicity: rare liver enzyme elevation requiring monitoring. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Persistent vomiting: leading to dehydration or electrolyte imbalance. - Rare neutropenia: significant drop in white blood cells. - Unexplained fever: may indicate systemic infection.

What precautions apply to Nystatin?

Before using Nystatyna Teva, consider the following safety measures. - Pregnancy: consult a healthcare professional; safety data are limited. - Breastfeeding: discuss potential risks with a physician. - Renal impairment: use with caution as excretion may be reduced. - Known hypersensitivity: avoid if allergic to nystatin or other polyenes. - Concomitant medications: review all drugs to identify potential interactions. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

What does Nystatin interact with?

Nystatyna Teva has a low potential for drug‑drug interactions, but certain combinations warrant attention.

Major Interactions (Avoid): - None reported: no clinically significant major interactions have been identified.

Moderate Interactions (Monitor Closely): - Oral antibiotics: may alter gut flora and affect Candida balance. - Other antifungal agents: monitor for additive gastrointestinal irritation. - Antacids: could affect dissolution and absorption of the oral formulation. - Probiotics: may reduce antifungal efficacy, requiring clinical observation. - Immunosuppressants: increased risk of opportunistic infections; monitor patient closely.

Frequently asked questions

What conditions is Nystatyna Teva used to treat?+
Nystatyna Teva contains nystatin, which is indicated for the treatment of oral candidiasis (thrush) and esophageal candidiasis caused by Candida species. It may also be used to manage denture‑related stomatitis where Candida overgrowth contributes to inflammation.
How does nystatin work against fungal infections?+
Nystatin binds to ergosterol in the fungal cell membrane, forming pores that increase membrane permeability. This disrupts the integrity of the cell, causing leakage of essential intracellular components and leading to fungal cell death, while remaining poorly absorbed systemically.
What is the usual dose of Nystatyna Teva?+
The dosage of Nystatyna Teva is determined by the prescribing clinician based on the patient’s age, weight, severity of infection, and specific formulation. The prescriber will provide the appropriate dosing schedule and duration of therapy.
Is Nystatyna Teva safe to use during pregnancy or breastfeeding?+
Safety data for nystatin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nystatyna Teva.
How do I order Nystatyna Teva from GNH USA?+
To order Nystatyna Teva, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Nystatyna Teva compare with other antifungal treatments?+
Nystatin is a polyene antifungal that acts locally in the gastrointestinal tract and has minimal systemic absorption, making it suitable for mucosal Candida infections. Unlike azole antifungals, it does not inhibit cytochrome P450 enzymes, resulting in fewer drug‑drug interactions, but it is limited to topical or oral use for superficial infections.
What are the recommended storage conditions for Nystatyna Teva?+
Nystatyna Teva should be stored at temperatures below 25 °C, in its original container, protected from moisture and direct sunlight. Keeping the product in a cool, dry place helps maintain its stability and potency throughout its shelf life.
How is Nystatyna Teva administered?+
Nystatyna Teva is taken orally, typically as a suspension or tablet, as directed by the prescribing clinician. The medication should be swallowed or, if a suspension, swished around the mouth and then swallowed to ensure contact with the affected mucosal surfaces.
What are the most serious risks associated with Nystatyna Teva?+
Although rare, serious adverse reactions can include severe allergic responses such as anaphylaxis, significant liver enzyme elevations indicating hepatotoxicity, and rare severe skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, rash, or persistent vomiting.
Who should not use Nystatyna Teva?+
Individuals with a known hypersensitivity to nystatin or other polyene antifungals should avoid using Nystatyna Teva. Additionally, patients with severe renal impairment should use the product only under close medical supervision, and pregnant or breastfeeding women should consult their healthcare provider before initiating therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Nystatin
Route
Oral Use
Manufacturer
Teva Pharmaceuticals Polska Sp. Z O.O.
Origin
EU

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