Nystatin Acis

Nystatin, the active ingredient in Nystatin Acis, is a polyol polyfungi presented as a pharmaceutical preparation for oral use. It treats fungal infections of the mouth, skin and gastrointestinal tract in both adults and children.

GNH USA supplies Nystatin Acis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Nystatin Acis is an antifungal agent used to manage infections caused by susceptible Candida species.

- Oral thrush: reduces fungal load and relieves symptoms in the mouth and throat. - Esophageal candidiasis: helps clear infection and improve swallowing. - Cutaneous candidiasis: treats skin fungal infections such as diaper rash and intertrigo. - Intestinal candidiasis: controls overgrowth of Candida in the gastrointestinal tract. - Prophylaxis in immunocompromised patients: prevents fungal colonisation during high‑risk periods.

Nystatin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset after oral administration. - Vomiting: occasional expulsion of stomach contents. - Abdominal cramps: transient discomfort in the abdomen. - Diarrhea: loose stools during treatment. - Skin rash: localized redness or irritation. - Itching: mild pruritus at the application site.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate medical attention. - Hepatotoxicity: signs of liver injury such as jaundice. - Nephrotoxicity: impaired kidney function, especially with high doses. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Persistent gastrointestinal upset: prolonged vomiting or diarrhea. - Hematologic abnormalities: rare blood cell count changes.

When using Nystatin Acis, consider the following safety measures.

- Pregnancy: use only if the potential benefit justifies the potential risk to the fetus. - Breastfeeding: caution advised as small amounts may be excreted in breast milk. - Renal impairment: monitor kidney function and adjust therapy if needed. - Hepatic impairment: assess liver function before and during treatment. - Drug interactions: review concomitant medications for possible interactions. - Store at ambient temperature: keep in the original packaging, protect from moisture and light.

Nystatin Acis may interact with other medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid): - Concurrent nephrotoxic drugs: increased risk of kidney injury. - Co‑administration with other polyene antifungals: heightened toxicity potential. - Systemic corticosteroids: may reduce antifungal efficacy.

Moderate Interactions (Monitor Closely): - Antacids: may affect oral absorption of the drug. - Broad‑spectrum antibiotics: can alter normal flora and affect fungal balance. - Oral contraceptives: possible reduction in contraceptive effectiveness.