GNH USA

Europe — EMA

Nutrineal Peritoneal Dialysis 4

GNH USA supplies Nutrineal Peritoneal Dialysis 4 (amino acid solution), a parenteral nutrition product for peritoneal dialysis patients requiring amino acid

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Nutrineal Peritoneal Dialysis 4, is a parenteral nutrition – amino acid solution presented as a solution for intraperitoneal use. It provides essential and non‑essential amino acids to support protein synthesis and nitrogen balance in patients receiving peritoneal dialysis.

GNH USA supplies Nutrineal Peritoneal Dialysis 4 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and dialysis clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Nutrineal Peritoneal Dialysis 4, an amino acid solution for peritoneal dialysis, is used to address protein‑energy malnutrition in dialysis patients. - Peritoneal dialysis patients: provides amino acid supplementation to maintain nitrogen balance. - Protein‑energy malnutrition in dialysis: helps prevent or treat malnutrition. - Chronic kidney disease on dialysis: supports protein synthesis and overall nutritional status.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Common Side Effects: - Abdominal discomfort: mild irritation of the peritoneal cavity. - Nausea: transient feeling of queasiness after exchange. - Transient hyperglycemia: slight rise in blood glucose levels. - Peritoneal irritation: mild inflammation at the infusion site. Serious or Rare Side Effects: - Allergic reaction (anaphylaxis): severe hypersensitivity requiring immediate medical attention. - Peritonitis: infection of the peritoneal cavity. - Electrolyte imbalance: significant disturbances in serum potassium, sodium or calcium levels.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Before initiating therapy, assess the patient’s nutritional status and protein requirements. - Monitor serum electrolytes: watch for changes in potassium, sodium, and calcium. - Check peritoneal membrane function: ensure adequate transport characteristics. - Avoid in patients with known hypersensitivity to any amino acid component. - Adjust dosing in severe hepatic impairment: consider reduced nitrogen load. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Major Interactions (Avoid): - Concurrent high‑protein parenteral nutrition: risk of excess nitrogen load. - Use with nephrotoxic drugs: may exacerbate kidney stress. Moderate Interactions (Monitor Closely): - Electrolyte‑containing solutions: monitor serum levels for additive effects. - Insulin or oral hypoglycemics: may need dose adjustment due to glucose load. - Other amino acid solutions: avoid duplication to prevent overload.

Frequently asked questions

What is Nutrineal Peritoneal Dialysis 4 used for?+
Nutrineal Peritoneal Dialysis 4 is an amino acid solution designed for peritoneal dialysis patients. It provides essential and non‑essential amino acids to support protein synthesis and help prevent protein‑energy malnutrition associated with long‑term dialysis therapy.
How does the amino acid mixture work?+
The formulation delivers a balanced profile of essential and non‑essential amino acids directly into the peritoneal cavity. These amino acids are absorbed across the peritoneal membrane into the bloodstream, supplying substrates for protein synthesis and maintaining nitrogen balance in the patient.
What is the usual dose?+
The prescribed dose is determined by the treating physician based on the patient’s nutritional status, dialysis prescription, and laboratory parameters. Dosing is individualized and administered via the peritoneal dialysis exchange as directed by the clinician.
Is it safe in pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been established. The product should be used only if the potential benefit justifies the potential risk to the mother and fetus, and it must be under close medical supervision.
How do I order Nutrineal Peritoneal Dialysis 4 from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does it compare with other peritoneal dialysis amino acid solutions?+
Nutrineal provides a comprehensive blend of ten amino acids in concentrations optimized for intraperitoneal use, matching or exceeding the amino acid profile of many competing formulations. Choice often depends on regional availability, cost, and specific patient tolerance.
What are the storage requirements?+
Store at ambient temperature, below 25 °C, in the original sealed container. Protect from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze the solution; keep it out of reach of children.
How is the product administered?+
The solution is added to the peritoneal dialysis exchange bag and introduced into the peritoneal cavity during a standard dialysis dwell. Administration follows the prescribed exchange volume and dwell time set by the healthcare provider.
What are the most serious risks to watch for?+
Serious adverse events include allergic reactions such as anaphylaxis, peritonitis, and significant electrolyte disturbances. Patients should be monitored for signs of hypersensitivity, abdominal pain, fever, or abnormal laboratory values, and medical attention should be sought promptly if they occur.
Who should not use Nutrineal Peritoneal Dialysis 4?+
Patients with known hypersensitivity to any of the amino acids in the formulation, those with severe hepatic impairment, or individuals with uncontrolled electrolyte imbalances should not receive the product unless a physician determines that the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intraperitoneal Use
Manufacturer
Vantive Belgium
Origin
EU