Nurofen Retard (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Retard, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a delayed‑release oral tablet for systemic use. It relieves pain, reduces fever and decreases inflammation in adults and children when appropriate. GNH USA supplies Nurofen Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen Retard is an NSAID that acts on inflammatory pathways to provide symptomatic relief in several common conditions. - Dental pain: reduces pain and swelling after dental procedures. - Musculoskeletal pain: alleviates aches associated with sprains, strains and arthritis. - Fever: lowers elevated body temperature in acute febrile states. - Dysmenorrhoea: eases menstrual cramps and associated discomfort. - Headache: mitigates tension‑type and mild migraine headaches.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache unrelated to the treated condition. - Dizziness: light‑headed sensation, especially on standing. - Rash: mild skin erythema or itching. - Elevated blood pressure: modest rise in systolic/diastolic values.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: black stools or vomiting blood. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Renal impairment: reduced urine output or swelling. - Hepatotoxicity: jaundice or abnormal liver enzymes. - Anaphylaxis: sudden difficulty breathing, swelling of face or throat.

Before initiating therapy with Nurofen Retard, consider the following safety measures: - Assess renal function: patients with chronic kidney disease should be evaluated. - Review cardiovascular risk: NSAIDs may increase blood pressure and cardiovascular events. - Check gastrointestinal history: prior ulcer disease raises bleeding risk. - Avoid use in late pregnancy: NSAIDs can affect fetal circulation. - Monitor in asthma: may trigger bronchospasm in sensitive individuals. - Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Ibuprofen can interact with several drug classes, altering efficacy or safety profiles.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - Selective serotonin reuptake inhibitors (SSRIs): increased gastrointestinal bleeding risk. - ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - Diuretics: may potentiate renal insufficiency. - Lithium: ibuprofen can raise serum lithium levels. - Methotrexate: reduced renal clearance may increase toxicity. - Corticosteroids: combined use raises ulcer risk.