Nurofen Rapid (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Rapid, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a oral tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children when appropriate.

GNH USA supplies Nurofen Rapid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen Rapid is an NSAID that provides analgesic and antipyretic effects across several common conditions.

- Headache: Reduces pain intensity and improves comfort. - Dental pain: Alleviates post‑extraction or procedural discomfort. - Musculoskeletal pain: Diminishes aches associated with strains, sprains and minor arthritis. - Fever: Lowers elevated body temperature in acute febrile states. - Menstrual cramps: Relieves dysmenorrhoeic pain during menstruation.

Adverse reactions to ibuprofen may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache: mild, transient headache. - Dizziness: occasional light‑headed feeling. - Rash: mild skin irritation or erythema. - Elevated blood pressure: modest rise in systolic/diastolic values.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines. - Renal impairment: acute kidney injury, especially with dehydration. - Hepatic injury: elevated liver enzymes or hepatitis. - Severe hypersensitivity: anaphylaxis, angio‑edema or Stevens‑Johnson syndrome. - Cardiovascular events: increased risk of heart attack or stroke.

When using Nurofen Rapid, certain safety considerations are important to minimise risk.

- Assess renal function: patients with chronic kidney disease should be evaluated before use. - Monitor gastrointestinal health: individuals with a history of ulcers or bleeding require caution. - Evaluate cardiovascular risk: use prudently in patients with hypertension or heart disease. - Avoid use in late pregnancy: ibuprofen is contraindicated during the third trimester. - Check for drug interactions: review concomitant medications for potential conflicts. - Store at ambient temperature: keep below 25°C, retain in original packaging and protect from moisture.

Ibuprofen may interact with several medication classes, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - High‑dose aspirin aspirin: increased gastrointestinal toxicity. - Selective COX‑2 inhibitors (e.g., celecoxib): additive renal and cardiovascular effects.

Moderate Interactions (Monitor Closely): - ACE inhibitors, ARBs: possible reduction in antihypertensive effect and renal function. - Diuretics (loop or thiazide): enhanced risk of kidney injury. - Lithium: ibuprofen may raise serum lithium levels. - Methotrexate: decreased clearance leading to toxicity.