Nurofen Pre Deti (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Pre Deti, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a rectal formulation for rectal use. It provides antipyretic, analgesic and anti‑inflammatory effects, making it suitable for reducing fever and relieving mild to moderate pain, especially in pediatric patients.

GNH USA supplies Nurofen Pre Deti as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

Fever: Reduces elevated body temperature in children. Pain: Relieves mild to moderate pain such as headache, toothache, or musculoskeletal discomfort. Inflammation: Decreases inflammation associated with minor injuries or conditions.

Common Side Effects: - Nausea: Mild stomach upset or queasiness. - Dyspepsia: Indigestion or heartburn. - Headache: Transient mild headache. - Dizziness: Light‑headed feeling. - Rash: Minor skin irritation. - Diarrhoea: Loose stools.

Serious or Rare Side Effects: - Gastrointestinal bleeding: Blood in stool or vomit. - Peptic ulcer: Persistent stomach pain. - Severe allergic reaction: Swelling, hives, or difficulty breathing. - Liver injury: Jaundice or elevated liver enzymes. - Kidney impairment: Reduced urine output or swelling. - Stevens‑Johnson syndrome: Severe skin blistering.

Before using Nurofen Pre Deti, consider the following precautions: - Allergies: Avoid if you have a known hypersensitivity to ibuprofen or other NSAIDs. - Gastrointestinal risk: Use with caution if you have a history of ulcers, bleeding, or chronic stomach irritation. - Cardiovascular health: Limit use in patients with hypertension, heart disease, or stroke risk. - Renal function: Monitor kidney function in patients with existing renal impairment. - Pregnancy and lactation: Consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: Keep below 25°C, in the original packaging, protected from moisture and direct sunlight.

Ibuprofen can interact with several medicines; monitor accordingly.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): Increased risk of serious bleeding. - Other NSAIDs or aspirin: Heightened gastrointestinal toxicity. - Corticosteroids: Elevated risk of ulceration. - ACE inhibitors or ARBs: Potential reduction in renal function. - Lithium: Increased lithium serum levels.

Moderate Interactions (Monitor Closely): - Antihypertensives (e.g., beta‑blockers): May diminish blood pressure control. - Diuretics: Possible reduction in diuretic efficacy and renal perfusion. - Methotrexate: Decreased clearance leading to toxicity. - SSRIs or SNRIs: Slightly increased bleeding tendency. - Alcohol: Enhanced gastrointestinal irritation and bleeding risk.