GNH USA

Europe — EMA

Nurofen Pour Enfants Suppo (Ibuprofen)

GNH USA supplies Nurofen Pour Enfants Suppo (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain relief, fever reduction and inflammation in children.

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What is Ibuprofen?

Ibuprofen, the active ingredient in Nurofen Pour Enfants Suppo, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a rectal suppository for pediatric use. It treats pain, fever and inflammation in children. GNH USA supplies Nurofen Pour Enfants Suppo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen used for?

Ibuprofen acts on inflammatory pathways to provide analgesic, antipyretic and anti‑inflammatory benefits in children. - Pain relief: reduces mild to moderate pain associated with common childhood ailments. - Fever reduction: lowers elevated body temperature in febrile illnesses. - Inflammation: alleviates inflammatory discomfort such as post‑vaccination soreness.

What are the side effects of Ibuprofen?

Adverse reactions may occur with ibuprofen suppositories and are grouped by frequency.

Common Side Effects: - Rectal irritation or discomfort - Mild stomach upset or dyspepsia - Nausea - Dizziness - Headache - Skin rash

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reaction (anaphylaxis) - Acute kidney injury or impaired renal function - Elevated liver enzymes or hepatic injury - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Hematologic abnormalities such as thrombocytopenia

What precautions apply to Ibuprofen?

When using ibuprofen suppositories in children, several safety considerations apply. - Age restriction: Use only in children as directed by a healthcare professional. - Allergy check: Avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs. - Medical conditions: Exercise caution in children with asthma, renal or hepatic impairment. - Drug interactions: Review concomitant medications for potential interactions. - Storage: Store at room temperature below 25°C: keep in the original pack, protect from moisture.

What does Ibuprofen interact with?

Ibuprofen may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs: additive gastrointestinal and renal toxicity. - ACE inhibitors or ARBs: possible reduction in renal function. - Lithium: elevated lithium levels. - Methotrexate: enhanced toxicity.

Moderate Interactions (Monitor Closely): - Diuretics: potential renal effects. - SSRIs or SNRIs: heightened bleeding risk. - Corticosteroids: increased risk of ulceration. - Antidiabetic agents: possible alteration of glycaemic control. - Allopurinol: rare rash reactions.

Frequently asked questions

What is Nurofen Pour Enfants Suppo used for?+
Nurofen Pour Enfants Suppo is an ibuprofen rectal suppository indicated for the relief of mild to moderate pain, reduction of fever, and alleviation of inflammation in pediatric patients.
How does ibuprofen work?+
Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins that mediate pain, fever, and inflammation.
What is the usual dose?+
The dose is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. Patients should follow the prescriber’s instructions precisely.
Is it safe in pregnancy or breastfeeding?+
Safety of this pediatric rectal formulation during pregnancy and lactation has not been established. It should be used only if clearly indicated by a qualified healthcare provider.
How do I order Nurofen Pour Enfants Suppo from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does it compare with acetaminophen (paracetamol)?+
Ibuprofen provides analgesic, antipyretic and anti‑inflammatory effects, whereas acetaminophen offers analgesic and antipyretic activity without significant anti‑inflammatory action. Choice depends on the specific clinical need and safety profile.
How should the product be stored?+
Store at room temperature below 25 °C, keep the suppositories in the original packaging, and protect them from moisture and direct sunlight to maintain stability.
How is the suppository administered?+
The suppository is inserted rectally, preferably after a bowel movement. The child should be placed in a comfortable position, and the suppository gently pushed in until fully seated.
What are the most serious risks to watch for?+
Serious adverse reactions may include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, kidney impairment, and rare skin conditions like Stevens‑Johnson syndrome. Immediate medical attention is required if any of these occur.
Who should not use this product?+
Children with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration, severe renal or hepatic impairment, or certain asthma phenotypes should avoid using this product unless advised otherwise by a clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Rectal Use
Manufacturer
Reckitt Benckiser Healthcare (Belgium) Sa/Nv
Origin
EU

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