Nurofen Non-Aqua (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Non-Aqua, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects and is commonly used to relieve mild to moderate pain, reduce fever, and manage inflammation in adults and children when appropriate under medical guidance and appropriate dosing.

GNH USA supplies Nurofen Non-Aqua as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide and other healthcare providers through reliable distribution networks.

Ibuprofen, an NSAID, acts on inflammatory pathways to provide relief in several common conditions.

- Mild to moderate pain: reduces pain intensity in headaches, dental pain, menstrual cramps and musculoskeletal discomfort. - Fever: lowers elevated body temperature in febrile states. - Inflammatory conditions: diminishes swelling and stiffness associated with arthritis and other inflammatory disorders.

Ibuprofen may cause a range of adverse reactions, varying from mild and frequent to rare but serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache or dizziness: transient sensations of light‑headedness. - Skin reactions: mild rash or itching. - Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Renal impairment or acute kidney injury. - Severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. - Hepatic injury: elevated liver enzymes or hepatitis. - Cardiovascular events: increased risk of thrombotic episodes in high‑risk individuals.

When using ibuprofen, certain safety considerations should be observed.

- Assess renal function: avoid in severe renal impairment. - Monitor gastrointestinal risk: use with food or consider protective agents in high‑risk patients. - Avoid in known hypersensitivity to NSAIDs or aspirin. - Use caution in pregnancy: especially avoid in the third trimester. - Review concomitant anticoagulant therapy: avoid unless medically supervised. - Store at ambient temperature: keep below 25°C, in the original packaging, and protect from moisture.

Ibuprofen can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened risk of ulceration. - ACE inhibitors or ARBs: possible reduction in renal function. - Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely): - Diuretics: potential for reduced antihypertensive effect. - Methotrexate: decreased clearance leading to toxicity. - SSRIs: modest increase in bleeding tendency.