Nurofen Lysine (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Lysine, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.

GNH USA supplies Nurofen Lysine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts systemically to modulate inflammatory pathways and is indicated for several common conditions: - Pain: provides relief of mild to moderate nociceptive pain such as headache, dental or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infection or inflammatory states. - Inflammation: reduces swelling and tenderness in conditions like arthritis or soft‑tissue injury.

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Nausea: mild gastrointestinal upset that often resolves without intervention. - Dyspepsia: discomfort or burning in the upper abdomen. - Headache: transient tension‑type headache. - Dizziness: occasional light‑headed sensation. - Rash: mild skin erythema or itching. - Diarrhoea: loose stools that are usually self‑limiting.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration: may present as black stools or abdominal pain. - Renal impairment: reduced urine output or swelling. - Severe allergic reaction: hives, swelling of face or throat, difficulty breathing. - Liver enzyme elevation: abnormal liver function tests. - Stevens‑Johnson syndrome: painful skin blistering and mucosal involvement. - Anaphylaxis: rapid onset of systemic allergic symptoms requiring emergency care.

Before using Nurofen Lysine, consider the following safety measures: - Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding. - Use the lowest effective dose: limit duration to the shortest period needed for symptom control. - Avoid in known hypersensitivity: discontinue if allergic reactions occur. - Caution in renal or hepatic impairment: monitor kidney and liver function where pre‑existing disease exists. - Avoid concomitant anticoagulants: increased risk of bleeding when combined with warfarin or similar agents. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - Other NSAIDs or high‑dose aspirin: additive gastrointestinal toxicity. - ACE inhibitors (e.g., enalapril): potential reduction in renal function.

Moderate Interactions (Monitor Closely): - Diuretics (e.g., furosemide): may diminish diuretic efficacy and affect kidney function. - Methotrexate: ibuprofen can increase methotrexate serum levels. - Selective serotonin reuptake inhibitors (e.g., sertraline): modestly increased bleeding risk.