Nurofen Lysine (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Lysine, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain, reduce fever, and decrease inflammation in adults and children.

GNH USA supplies Nurofen Lysine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen Lysine is an NSAID that acts on inflammatory pathways to provide symptomatic relief in several common conditions. - Headache: alleviates pain and reduces associated discomfort. - Dental pain: helps control postoperative or tooth‑ache pain. - Musculoskeletal pain: eases aches, strains and minor joint discomfort. - Fever: lowers elevated body temperature in febrile states. - Menstrual cramps: reduces uterine cramping and associated pelvic pain.

Adverse reactions to ibuprofen may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache unrelated to the treated condition. - Dizziness: light‑headed sensation, especially on standing. - Rash: mild skin erythema or itching. - Elevated blood pressure: modest rise in systolic/diastolic values.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding. - Renal impairment: acute kidney injury, especially with dehydration. - Hepatotoxicity: elevated liver enzymes or hepatitis. - Anaphylaxis: severe allergic reaction with airway compromise. - Stevens‑Johnson syndrome: rare severe skin reaction.

When using Nurofen Lysine, consider the following safety measures: - Assess renal function: avoid use in patients with severe kidney impairment. - Evaluate cardiovascular risk: use cautiously in individuals with hypertension or heart disease. - Review gastrointestinal history: patients with ulcers or bleeding disorders should use only under medical supervision. - Monitor pregnancy status: avoid in the third trimester and use only if clearly needed during earlier trimesters. - Check for drug allergies: discontinue if signs of hypersensitivity appear. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture.

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: additive gastrointestinal toxicity. - Selective COX‑2 inhibitors (e.g., celecoxib): heightened cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce antihypertensive effect and affect kidney function. - Diuretics: potential for reduced renal perfusion. - Lithium: ibuprofen may increase serum lithium levels. - Methotrexate: decreased clearance leading to toxicity. - SSRIs: combined use can raise bleeding risk.