GNH USA

Europe — EMA

Nurofen Junior (Ibuprofen)

GNH USA supplies Nurofen Junior (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain relief, fever reduction and inflammation.

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What is Ibuprofen?

Ibuprofen, the active ingredient in Nurofen Junior, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It provides analgesic, antipyretic and anti‑inflammatory effects for children experiencing pain, fever or mild inflammation. GNH USA supplies Nurofen Junior as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen used for?

Nurofen Junior contains ibuprofen, an NSAID that reduces prostaglandin synthesis to alleviate discomfort and fever in pediatric patients. - Pain relief: eases mild to moderate pain such as teething or sore throat. - Fever reduction: lowers elevated body temperature associated with infections. - Inflammation: helps diminish localized swelling caused by minor injuries or inflammatory conditions.

What are the side effects of Ibuprofen?

Adverse reactions may occur with ibuprofen suppositories, although many are mild and transient.

Common Side Effects: - Gastrointestinal discomfort: mild abdominal pain or nausea. - Local irritation: redness or mild burning at the insertion site. - Headache: occasional tension‑type headache. - Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling, or anaphylaxis. - Gastrointestinal bleeding: black stools or vomiting blood. - Renal impairment: reduced urine output or swelling in the extremities.

What precautions apply to Ibuprofen?

When using Nurofen Junior, consider the following safety measures. - Age restriction: only for children as directed by a healthcare professional. - Existing conditions: avoid if the child has known NSAID hypersensitivity, active gastrointestinal ulcer, or severe renal disease. - Concomitant medications: review use with other NSAIDs, anticoagulants, or corticosteroids. - Pregnancy and lactation: consult a physician before use in pregnant or breastfeeding mothers. - Storage: Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen interact with?

Ibuprofen may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: possible reduction in renal function. - Selective serotonin reuptake inhibitors (SSRIs): modestly increased bleeding risk. - Methotrexate: potential for increased toxicity at high doses.

Frequently asked questions

What is Nurofen Junior used for?+
Nurofen Junior is an ibuprofen‑based suppository designed for rectal administration in children. It provides relief from mild to moderate pain, helps lower fever, and reduces inflammation associated with common childhood conditions such as teething, sore throat, or minor injuries.
How does ibuprofen work in Nurofen Junior?+
Ibuprofen blocks the cyclooxygenase (COX‑1 and COX‑2) enzymes, which are needed to produce prostaglandins. By lowering prostaglandin levels, the drug diminishes inflammation, reduces the hypothalamic set‑point for temperature, and lessens pain signaling, delivering analgesic, antipyretic, and anti‑inflammatory effects.
What is the usual dose of Nurofen Junior?+
The appropriate dose of Nurofen Junior is determined by a qualified prescriber based on the child’s age, weight, and clinical condition. Healthcare professionals calculate the exact amount to ensure safe and effective therapy, and the dosing schedule should be followed exactly as advised.
Is Nurofen Junior safe during pregnancy or breastfeeding?+
Use of ibuprofen in pregnancy or while breastfeeding should only be considered after consulting a physician. Generally, ibuprofen is avoided in the third trimester of pregnancy and used with caution during lactation, as it may affect fetal development or be transferred in breast milk.
How do I order Nurofen Junior from GNH USA?+
To request Nurofen Junior, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Nurofen Junior compare with other pediatric pain relievers?+
Compared with acetaminophen (paracetamol), ibuprofen offers both analgesic and anti‑inflammatory benefits and can reduce fever more effectively in some cases. However, ibuprofen carries a higher risk of gastrointestinal irritation and should be avoided in children with certain medical conditions, whereas acetaminophen has a different safety profile.
How should Nurofen Junior be stored and handled?+
Store Nurofen Junior at ambient temperature, ideally below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged or the suppository appears discolored.
How is Nurofen Junior administered?+
Nurofen Junior is administered rectally. The suppository is gently inserted into the child’s rectum, preferably after a mild bowel movement, using clean hands or a disposable applicator if provided. Follow the prescriber’s instructions for positioning and ensure the child remains still for a few minutes to allow absorption.
What are the most serious risks associated with Nurofen Junior?+
Serious risks include severe allergic reactions such as anaphylaxis, gastrointestinal bleeding, and renal impairment, especially in children with pre‑existing kidney disease or those receiving other nephrotoxic drugs. Immediate medical attention is required if symptoms like rash, vomiting blood, or reduced urine output occur.
Who should not use Nurofen Junior?+
Children with known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal ulcers, severe renal or hepatic impairment, or who are receiving anticoagulant therapy should avoid Nurofen Junior unless a healthcare professional explicitly advises otherwise.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Rectal Use
Manufacturer
Reckitt Benckiser Deutschland Gmbh
Origin
EU

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