Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug presented as a strength/form for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to relieve pain and reduce fever. It is commonly used for: - Headache: provides relief from tension‑type and migraine‑associated pain. - Dental pain: reduces post‑extraction or procedure discomfort. - Musculoskeletal pain: eases aches from sprains, strains and arthritis. - Fever: lowers elevated body temperature in acute infections. - Menstrual cramps: diminishes dysmenorrhoeic pain.

Adverse reactions may range from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache: mild, transient headache. - Dizziness: occasional light‑headed feeling. - Rash: mild skin irritation or erythema. - Elevated blood pressure: modest rise in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe skin reactions such as Stevens‑Johnson syndrome. - Renal impairment or acute kidney injury. - Anaphylaxis: life‑threatening allergic response. - Hepatotoxicity: liver enzyme elevations or injury.

Before using Nurofen, consider the following safety measures: - Cardiovascular risk: avoid if you have a history of heart disease or stroke. - Gastrointestinal history: caution in patients with ulcers or chronic gastritis. - Renal function: monitor kidney health in those with existing impairment. - Pregnancy and lactation: consult a healthcare professional before use. - Concomitant medications: review all current drugs for potential interactions. - Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Ibuprofen may interact with several drug classes. Review the following:

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive renal and cardiovascular effects.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive efficacy. - Diuretics: risk of reduced renal perfusion. - Lithium: increased serum lithium levels. - Methotrexate: decreased renal clearance leading to toxicity.