Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a 200 mg tablet for oral use. It relieves pain, reduces fever and eases inflammation in adults and children when directed by a healthcare professional.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to provide symptomatic relief in several common conditions. - Headache: reduces pain intensity and associated discomfort. - Dental pain: alleviates post‑extraction or procedural soreness. - Musculoskeletal pain: eases aches from strains, sprains and minor arthritis. - Fever: lowers elevated body temperature in febrile states. - Menstrual discomfort: diminishes cramps and associated pelvic pain.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache unrelated to the treated condition. - Dizziness: occasional light‑headedness or vertigo. - Rash: mild skin erythema or itching. - Elevated blood pressure: modest rise in systolic/diastolic values.

Serious or Rare Side Effects: - Gastrointestinal bleeding: melena, hematemesis or severe abdominal pain. - Renal impairment: sudden decrease in urine output or swelling. - Hepatic injury: jaundice, dark urine or elevated liver enzymes. - Severe allergic reaction: anaphylaxis, facial swelling or airway compromise. - Stevens‑Stevenson‑Johnson syndrome: widespread skin blistering and mucosal involvement.

When using ibuprofen, consider the following safety measures: - Assess medical history: identify any prior gastrointestinal ulcer, bleeding or renal disease. - Evaluate cardiovascular risk: monitor patients with hypertension or heart disease. - Review concomitant medications: avoid concurrent use with other NSAIDs or anticoagulants unless directed. - Limit duration: use the lowest effective dose for the shortest period required. - Pregnancy and lactation: consult a healthcare professional before use in pregnancy or while breastfeeding. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Ibuprofen may interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective COX‑2 inhibitors (e.g., celecoxib): additive renal and gastrointestinal toxicity. - High‑dose aspirin aspirin: heightened gastrointestinal ulcer risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function. - Diuretics (e.g., furosemide): may diminish diuretic efficacy and affect kidney function. - Lithium: increased lithium serum levels and potential toxicity. - Methotrexate: reduced renal clearance leading to higher methotrexate concentrations. - Corticand