Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever and inflammation in adults and children when appropriate dosing is prescribed.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, batch traceability and regulatory support across all markets.

Ibuprofen, the active ingredient in Nurofen, works within the prostaglandin pathway to relieve various types of pain and inflammation.

- Headache: provides relief from tension‑type and mild migraine headaches. - Dental pain: reduces pain following dental procedures or toothache. - Musculoskeletal pain: alleviates pain from sprains, strains and minor injuries. - Fever: lowers elevated body temperature associated with infections. - Menstrual cramps: eases dysmenorrhea‑related discomfort.

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or heartburn. - Dizziness or mild headache. - Skin rash or mild itching. - Mild elevation of liver enzymes. - Fluid retention or mild edema.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Acute renal impairment or failure. - Severe allergic reactions such as anaphylaxis. - Hepatotoxicity with marked liver enzyme elevation. - Increased risk of cardiovascular events, including myocardial infarction or stroke.

Before using Nurofen, consider the following safety measures.

- Assess renal function: avoid in severe renal impairment. - Monitor gastrointestinal risk: use with food in patients with a history of ulcers. - Avoid in third‑trimester pregnancy: risk to the fetus. - Use cautiously with anticoagulants: increased bleeding risk. - Store at ambient temperature: keep in the original pack, protect from moisture.

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - High‑dose aspirin: increased gastrointestinal toxicity. - Lithium: reduced renal clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible reduction in renal function. - SSRIs: increased bleeding tendency. - Diuretics: risk of renal impairment.