Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is used to relieve pain, reduce fever, and lessen inflammation in a variety of conditions for adults and children when appropriate.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen (ibuprofen) acts on inflammatory pathways to provide symptomatic relief for several common conditions: - Pain: alleviates mild to moderate acute pain such as dental or post‑operative discomfort. - Fever: reduces elevated body temperature associated with infections or inflammatory states. - Inflammation: diminishes swelling and redness in conditions like sprains or bursitis. - Headache: eases tension‑type and migraine‑associated head pain. - Musculoskeletal pain: helps manage aches from arthritis, back strain, or over‑use injuries.

Adverse reactions may occur with ibuprofen use. They are categorized by frequency and severity.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain. - Headache: transient mild headache. - Dizziness: occasional light‑headed sensation. - Rash: mild skin erythema or itching. - Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions: angioedema, anaphylaxis. - Renal impairment: reduced kidney function. - Hepatotoxicity: liver enzyme elevations. - Cardiovascular events: increased risk of heart attack or stroke in high‑risk individuals.

When using Nurofen, consider the following safety measures: - Contraindications: avoid if you have a known hypersensitivity to ibuprofen or other NSAIDs. - Gastrointestinal risk: use with food or an antacid if you have a history of ulcer disease. - Cardiovascular caution: limit use in patients with hypertension, heart disease, or stroke risk. - Renal monitoring: assess kidney function in those with chronic kidney disease or dehydration. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Ibuprofen can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal protective effects. - Diuretics: potential for decreased kidney perfusion. - Lithium: ibuprofen can raise lithium serum levels. - Methotrexate: reduced clearance leading to toxicity. - SSRIs or other antidepressants: modestly increased bleeding risk.