Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever, and inflammation and is commonly used in adults and children for short‑term symptom relief. Its anti‑inflammatory action makes it suitable for conditions such as headache, dental pain, muscular aches, and fever associated with common colds.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Ibuprofen acts as a non‑selective cyclooxygenase inhibitor to relieve pain, fever and inflammation.

- Headache: relief of mild to moderate headache symptoms. - Dental pain: reduction of toothache and postoperative dental discomfort. - Musculoskeletal pain: alleviation of back, joint and muscle aches. - Fever: lowering of elevated body temperature associated with infections. - Menstrual cramps: easing of dysmenorrhea related discomfort.

Common Side Effects: - Stomach upset or dyspepsia. - Nausea or mild vomiting. - Heartburn or acid reflux. - Dizziness or light‑headedness. - Headache. - Diarrhoea.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions such as anaphylaxis or skin rash. - Liver injury indicated by jaundice or elevated enzymes. - Kidney impairment or acute renal failure. - Cardiovascular events including heart attack or stroke. - Blood disorders such as thrombocytopenia.

Before using Nurofen, consider the following precautions: - Assess renal function: avoid in severe renal impairment. - Known hypersensitivity: do not use if allergic to ibuprofen or other NSAIDs. - Asthma caution: may exacerbate bronchospasm in aspirin‑sensitive patients. - Alcohol consumption: limit intake as it increases gastrointestinal risk. - Duration of use: do not exceed recommended short‑term periods to reduce ulcer risk. - Store at room temperature: keep in the original pack, protect from moisture.

Ibuprofen may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - Corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function. - Lithium: ibuprofen can raise lithium serum levels. - Methotrexate: reduced clearance may lead to toxicity.