Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and treat inflammation in adults and children when appropriate.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts systemically to alleviate pain and inflammation across several common conditions.

- Headache: reduces pain intensity and associated discomfort. - Dental pain: provides relief after dental procedures or toothache. - Musculoskeletal pain: eases aches from sprains, strains, and back pain. - Fever: lowers elevated body temperature in febrile states. - Arthritis: diminishes joint inflammation and stiffness in osteoarthritis and rheumatoid arthritis.

Adverse reactions may occur with ibuprofen use.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or mild abdominal discomfort. - Headache: transient headache unrelated to the condition being treated. - Dizziness: occasional light‑headedness or vertigo.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage, especially with prolonged use. - Renal impairment: reduced kidney function or acute renal failure. - Allergic reactions: rash, itching, swelling, or anaphylaxis in hypersensitive individuals.

Before using ibuprofen, consider the following safety measures. - Assess renal function: avoid use in severe kidney disease without medical supervision. - Evaluate cardiovascular risk: limit use in patients with uncontrolled hypertension or heart disease. - Review gastrointestinal history: caution in those with a history of ulcers or bleeding. - Monitor pregnancy status: avoid in the third trimester and consult a physician during pregnancy. - Check concomitant medications: avoid combining with other NSAIDs or anticoagulants without guidance. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Ibuprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal protective effects. - Diuretics: potential for reduced diuretic efficacy and kidney function. - Lithium: ibuprofen may raise lithium levels, necessitating serum monitoring.