Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever, and inflammation in adults and children, and works by reducing the production of prostaglandins that mediate these symptoms. The medication is widely used for headache, dental pain, menstrual cramps, and musculoskeletal discomfort.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on the cyclooxygenase pathway to relieve symptoms across several common conditions.

Mild to moderate pain: provides relief from headaches, toothaches, menstrual cramps, and musculoskeletal discomfort. Fever: lowers elevated body temperature associated with infections or inflammatory states. Inflammation: reduces swelling and tenderness in conditions such as sprains or minor injuries. Arthritic pain: helps manage pain and stiffness in osteoarthritis.

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Stomach upset or heartburn. - Nausea or mild vomiting. - Dizziness or headache. - Skin rash or mild itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Acute kidney injury, especially with dehydration. - Severe allergic reactions such as anaphylaxis or angioedema.

Before using ibuprofen, consider the following safety measures.

Medical history review: assess for ulcer disease, kidney impairment, or cardiovascular risk. Pregnancy caution: avoid use in the third trimester unless advised by a healthcare professional. Dose minimization: use the lowest effective dose for the shortest duration. Drug combination warning: do not take with other NSAIDs, anticoagulants, or corticosteroids without medical guidance. Bleeding monitoring: watch for signs of gastrointestinal bleeding such as black stools or vomiting blood. Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

Ibuprofen can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin). - Other NSAIDs or aspirin. - Selective serotonin reuptake inhibitors (SSRIs). - Lithium therapy. - Systemic corticosteroids.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors (e.g., enalapril). - Diuretics (e.g., furosemide). - Methotrexate.