Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides temporary relief of pain, reduces fever, and helps manage inflammation in adults and children when appropriate.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen works by reducing inflammation and pain pathways, making it useful for several common conditions.

- Pain: provides temporary relief of mild to moderate pain such as headache, toothache, menstrual cramps, and musculoskeletal aches. - Fever: lowers elevated body temperature associated with infections or inflammatory processes. - Inflammation: helps control swelling and stiffness in conditions like minor sprains, strains, and arthritis flare‑ups.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Stomach upset or dyspepsia - Nausea or mild vomiting - Headache - Dizziness - Mild skin rash

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reaction (anaphylaxis) - Kidney injury or reduced renal function - Elevated liver enzymes or hepatitis - Cardiovascular events such as heart attack or stroke

Before using ibuprofen, consider the following safety measures.

- Medical History Review: assess for existing ulcers, kidney disease, or cardiovascular risk. - Take With Food: ingest with meals or milk to lessen gastric irritation. - Avoid Concomitant NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs. - Monitor Renal Function: especially in patients with dehydration or chronic kidney disease. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs: additive gastrointestinal toxicity. - Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely): - Diuretics: may reduce renal clearance of ibuprofen. - Methotrexate: potential for increased toxicity at high doses.