Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug presented as a 200 mg tablet for oral use. It relieves pain, reduces fever and eases inflammation in adults and children when recommended by a healthcare professional.

GNH USA supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen is an NSAID that acts on inflammatory pathways to provide symptomatic relief in several common conditions. - Headache: alleviates pain and reduces associated discomfort. - Dental pain: eases postoperative or acute toothache. - Musculoskeletal pain: diminishes aches from strains, sprains and minor arthritis. - Fever: lowers elevated body temperature in febrile states. - Menstrual cramps: reduces uterine cramping and associated pain.

Adverse reactions to ibuprofen may vary in frequency and severity.

Common Side Effects: - Gastro‑intestinal upset: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache unrelated to the condition being treated. - Dizziness: occasional light‑headedness or vertigo. - Rash: mild skin redness or itching. - Elevated blood pressure: modest rise in systolic or diastolic values.

Serious or Rare Side Effects: - Gastro‑intestinal bleeding or ulceration. - Severe allergic reactions: anaphylaxis, angioedema or bronchospasm. - Hepatic injury: marked elevation of liver enzymes or hepatitis. - Renal impairment: acute kidney injury or worsening chronic kidney disease. - Cardiovascular events: increased risk of myocardial infarction or stroke.

When using Nurofen, consider the following safety measures: - Assess renal function: avoid use in patients with severe kidney impairment. - Evaluate gastrointestinal risk: use with caution in those with a history of ulcers or bleeding. - Monitor blood pressure: check regularly in hypertensive individuals. - Pregnancy and lactation: limit use to the lowest effective dose and only when clearly needed. - Drug interactions: review concomitant medications for potential NSAID interactions. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture.

Ibuprofen can affect the activity of several other medicines. Careful management reduces the risk of adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk. - Lithium: ibuprofen may raise serum lithium concentrations.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: potential for decreased effectiveness and electrolyte imbalance. - Methotrexate: reduced clearance leading to toxicity.