Nurofen Flextin (Ibuprofen Sodium Dihydrate)

Ibuprofen, the active ingredient in Nurofen Flextin, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for systemic use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate. GNH USA supplies Nurofen Flextin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic and anti‑inflammatory effects. - Pain: alleviates mild to moderate acute pain such as headache, dental or musculoskeletal discomfort. - Fever: lowers elevated body temperature associated with infection or inflammatory conditions. - Inflammation: reduces swelling and stiffness in conditions like sprains, strains or minor arthritic flare‑ups.

Adverse reactions may range from mild to serious, depending on individual susceptibility and exposure.

Common Side Effects: - Nausea: mild stomach upset or queasiness. - Heartburn: burning sensation in the chest or throat. - Dyspepsia: general indigestion or abdominal discomfort. - Dizziness: transient light‑headed feeling. - Headache: mild to moderate head pain. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal bleeding: black stools or vomiting blood. - Severe allergic reaction: rash, swelling, or difficulty breathing. - Liver injury: jaundice or elevated liver enzymes. - Kidney impairment: reduced urine output or swelling. - Cardiovascular events: increased risk of heart attack or stroke. - Blood disorders: unexplained bruising or low platelet count.

Before using ibuprofen, consider the following safety measures. - Medical history review: assess for ulcer disease, heart failure, or renal impairment. - Lowest effective dose: use the smallest amount needed for symptom control. - Allergy check: avoid if known hypersensitivity to NSAIDs or aspirin. - Gastro‑intestinal monitoring: watch for signs of bleeding or ulceration. - Food intake: take with meals or milk to lessen stomach irritation. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: may worsen fluid loss and kidney effects. - Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.