Nurofen Express Forte (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Express Forte, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats mild to moderate pain, reduces fever, and helps manage inflammatory conditions in adults and children as directed.

GNH USA supplies Nurofen Express Forte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to relieve pain, fever and inflammation.

Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches. Fever: reduces elevated body temperature associated with infections or other causes. Inflammatory conditions: alleviates swelling and discomfort in conditions such as arthritis or minor injuries.

Adverse reactions may occur with ibuprofen use.

Common Side Effects: - Stomach upset or dyspepsia - Nausea or vomiting - Heartburn or acid reflux - Dizziness or light‑headedness - Headache - Mild rash or itching

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reactions (anaphylaxis, angioedema) - Kidney impairment or failure - Liver enzyme elevation or hepatitis - Cardiovascular events (e.g., hypertension, thrombotic events) - Severe skin reactions (e.g., Stevens‑Johnson syndrome)

Before using Nurofen Express Forte, consider the following precautions.

Assess gastrointestinal risk: evaluate history of ulcers or bleeding. Avoid in known hypersensitivity: do not use if allergic to ibuprofen or other NSAIDs. Use lowest effective dose: limit duration and amount to the minimum needed. Monitor renal function: especially in patients with kidney disease or dehydration. Avoid concomitant NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs. Store at ambient temperature: keep in the original pack, protect from moisture and light.

Ibuprofen may interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin) – increased bleeding risk - Other NSAIDs or aspirin – additive gastrointestinal toxicity - Corticosteroids – heightened ulcer risk - ACE inhibitors or ARBs – possible renal function decline - Lithium – increased lithium levels

Moderate Interactions (Monitor Closely): - Antihypertensives – may reduce blood pressure control - Diuretics – potential for reduced renal perfusion - Methotrexate – decreased clearance, risk of toxicity - SSRIs or SNRIs – modest increase in bleeding tendency - Oral hypoglycemics – possible alteration of glucose control