Nurofen Express (Ibuprofen Sodium Dihydrate)

Ibuprofen, the active ingredient in Nurofen Express, is a non‑steroidal anti‑inflammatory drug presented as an oral tablet for oral use. It is commonly employed to relieve pain, reduce fever, and lessen inflammation in a variety of short‑term conditions.

GNH USA supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Ibuprofen acts systemically to manage pain and inflammation associated with several common conditions. - Headache: provides relief from tension‑type and mild migraine pain. - Dental pain: reduces discomfort following dental procedures or toothache. - Musculoskeletal pain: eases aches from sprains, strains, and minor joint inflammation. - Menstrual cramps: lessens dysmenorrhea associated with uterine contractions. - Fever: helps lower elevated body temperature in adults.

Adverse reactions may occur with ibuprofen use and are categorized by frequency.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or mild abdominal pain. - Headache: transient headache unrelated to the condition being treated. - Dizziness: occasional light‑headedness or vertigo. - Rash: mild skin erythema or itching. - Elevated blood pressure: modest increase in systolic or diastolic pressure.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage requiring medical attention. - Renal impairment: reduced kidney function, especially with prolonged use. - Hepatotoxicity: abnormal liver enzymes or hepatitis. - Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome. - Cardiovascular events: increased risk of myocardial infarction or stroke in high‑risk patients.

Before using ibuprofen, consider the following safety measures. - Cardiovascular risk: avoid if you have a history of heart disease or stroke without medical advice. - Gastrointestinal history: caution in patients with ulcers, gastritis, or bleeding disorders. - Renal function: monitor kidney health in those with chronic kidney disease or dehydration. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Concomitant medications: review all current drugs for potential interactions. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive renal and cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function. - Diuretics: may enhance renal impairment. - Lithium: ibuprofen can raise serum lithium levels. - Methotrexate: reduced clearance leading to toxicity. - SSRIs or SNRIs: increased chance of gastrointestinal bleeding.