Nurofen Express (Ibuprofen Sodium Dihydrate)

Ibuprofen Sodium Dihydrate, the active ingredient in Nurofen Express, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed appropriately.

GNH USA supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen, an NSAID, acts on inflammatory pathways to relieve a range of common painful conditions.

- Headache: provides rapid relief of tension‑type and mild migraine headaches. - Dental pain: reduces postoperative discomfort after dental procedures. - Musculoskeletal pain: eases aches from sprains, strains and minor joint inflammation. - Menstrual pain: alleviates dysmenorrhoea associated with menstrual cramps. - Fever: lowers elevated body temperature in acute febrile states.

Common Side Effects: - Nausea: mild stomach upset may occur after ingestion. - Dyspepsia: occasional indigestion or heartburn. - Headache: transient headache in some users. - Dizziness: brief sensation of light‑headedness. - Diarrhoea: loose stools may be experienced.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or bleeding in the stomach or intestines. - Renal impairment: reduced kidney function, especially with prolonged use. - Cardiovascular events: increased risk of heart attack or stroke. - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare but serious skin reaction.

Before using Nurofen Express, consider the following precautions: - Contraindications: avoid if you have a known hypersensitivity to ibuprofen or other NSAIDs. - Gastro‑intestinal risk: use with food or antacids if you have a history of ulcers or GI bleeding. - Cardiovascular caution: limit use in patients with established heart disease or hypertension. - Renal function: monitor kidney health in individuals with chronic kidney disease. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding. - Store at ambient temperature: keep below 25°C, in the original pack, protected from moisture and direct sunlight.

Ibuprofen can interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened ulcer risk. - ACE inhibitors or ARBs: may reduce renal perfusion. - Lithium: ibuprofen can raise lithium serum levels.

Moderate Interactions (Monitor Closely): - Antihypertensives: possible reduction in blood pressure control. - Diuretics: may affect renal function. - Methotrexate: potential for increased toxicity. - SSRIs: modest increase in bleeding risk. - Alcohol: enhances gastrointestinal irritation.