GNH USA

Europe — EMA

Nurofen Express (Ibuprofen Sodium Dihydrate)

GNH USA supplies Nurofen Express (Ibuprofen), an NSAID for headache, toothache, menstrual, musculoskeletal pain and fever. Request a quote for global supply.

Ibuprofen Sodium Dihydrate

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1
Pack/s

What is Ibuprofen Sodium Dihydrate?

Ibuprofen, the active ingredient in Nurofen Express, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for common pains such as headache, toothache, menstrual discomfort, musculoskeletal aches and fever. GNH USA supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

What is Ibuprofen Sodium Dihydrate used for?

Nurofen Express, an NSAID, acts on inflammatory pathways to relieve pain and fever. - Headache: reduces pain intensity and associated discomfort. - Toothache: alleviates dental pain and inflammation. - Menstrual pain: eases cramps and lowers uterine discomfort. - Musculoskeletal pain: mitigates aches from strains, sprains or arthritis. - Fever: lowers elevated body temperature in acute febrile states.

What are the side effects of Ibuprofen Sodium Dihydrate?

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Stomach upset or dyspepsia. - Nausea or mild vomiting. - Dizziness or light‑headedness. - Headache. - Mild skin rash.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Severe allergic reactions such as anaphylaxis. - Liver enzyme elevations or hepatitis. - Acute kidney injury. - Stevens‑Johnson syndrome or toxic epidermal necrolysis.

What precautions apply to Ibuprofen Sodium Dihydrate?

Before using Nurofen Express, consider the following safety measures. - Assess medical history: check for ulcers, heart disease, kidney impairment, asthma or bleeding disorders. - Avoid concurrent NSAIDs: using multiple NSAIDs increases gastrointestinal and renal risk. - Limit alcohol intake: alcohol can exacerbate stomach irritation and bleeding. - Use the lowest effective dose for the shortest duration needed. - Store at room temperature: keep in the original pack, protect from moisture and heat.

What does Ibuprofen Sodium Dihydrate interact with?

Ibuprofen may interact with several medicines; monitor accordingly.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs: additive gastrointestinal toxicity. - Corticosteroids: increased ulcer formation.

Moderate Interactions (Monitor Closely): - ACE inhibitors: possible reduction in renal function. - Diuretics: may enhance renal effects of ibuprofen. - SSRIs: potential for increased bleeding tendency.

Frequently asked questions

What is Nurofen Express used for?+
Nurofen Express contains ibuprofen and is used to temporarily relieve mild to moderate pain such as headache, toothache, menstrual cramps, musculoskeletal aches, and to reduce fever. It is an over‑the‑counter option for short‑term symptom management in adults and children when appropriate.
How does ibuprofen work?+
Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces inflammation, pain signalling, and the hypothalamic set‑point that controls body temperature, providing analgesic, antipyretic and anti‑inflammatory effects.
What is the usual dose of Nurofen Express?+
The exact dose of Nurofen Express is determined by a healthcare professional or according to the product label. For over‑the‑counter use, adults typically take the recommended amount every 4‑6 hours, not exceeding the maximum daily limit, but the prescriber or label should be consulted for precise guidance.
Is Nurofen Express safe during pregnancy or breastfeeding?+
Safety data for ibuprofen in pregnancy are limited, especially in the third trimester, and it may affect fetal development. Breastfeeding mothers should also exercise caution as ibuprofen can pass into milk. Consultation with a physician or obstetrician is essential before use in these situations.
How do I order Nurofen Express from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nurofen Express compare with the main alternative drug class?+
The most common alternative for similar indications is paracetamol (acetaminophen). While both relieve pain and fever, ibuprofen additionally provides anti‑inflammatory action. Ibuprofen may be more effective for inflammatory pain, but it carries a higher risk of gastrointestinal and renal side effects compared with paracetamol.
How should Nurofen Express be stored and handled?+
Store Nurofen Express at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.
How is Nurofen Express administered?+
Nurofen Express is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew unless the product label specifically permits it.
What are the most serious risks associated with Nurofen Express?+
Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, liver injury, acute kidney damage, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of bleeding, rash, swelling, or sudden loss of kidney function.
Who should not use Nurofen Express?+
People with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, significant kidney or liver disease, or those in the third trimester of pregnancy should avoid Nurofen Express. A healthcare professional should evaluate suitability for all other individuals.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ibuprofen Sodium Dihydrate
Route
Oral Use
Manufacturer
Reckitt Benckiser (Poland) S.A.
Origin
EU

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