Nurofen Express (Ibuprofen Sodium)

Ibuprofen, the active ingredient in Nurofen Express, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a solid oral dosage form for short‑term, over‑the‑counter pain relief use. It helps reduce fever, alleviate mild to moderate pain and lessen inflammation in adults and children when used as directed.

GNH USA supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nurofen Express, an ibuprofen‑based NSAID, acts on inflammatory pathways to provide symptomatic relief in several common conditions. - Headache: eases tension‑type and mild migraine symptoms. - Dental pain: reduces discomfort after dental procedures or toothache. - Musculoskeletal pain: alleviates aches from strains, sprains and minor joint inflammation. - Fever: lowers elevated body temperature in febrile adults and children. - Menstrual cramps: lessens dysmenorrhoeic pain associated with menstrual cycles.

Adverse reactions to ibuprofen sodium may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache may occur. - Dizziness: light‑headed feeling or vertigo. - Skin rash: mild erythema or itching. - Elevated blood pressure: slight increase in systolic/diastolic readings.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe allergic reaction: anaphylaxis, angio‑edema. - Hepatic injury: elevated liver enzymes or hepatitis. - Renal impairment: acute kidney injury or reduced urine output. - Cardiovascular events: myocardial infarction or stroke.

When using Nurofen Express, consider the following safety measures: - Assess contraindications: avoid if known allergy to ibuprofen or other NSAIDs. - Monitor gastrointestinal health: patients with ulcer history should use caution. - Evaluate renal function: adjust use in those with chronic kidney disease. - Review cardiovascular risk: use the lowest effective dose for the shortest duration. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Ibuprofen sodium can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants: increased risk of bleeding with warfarin or direct oral anticoagulants. - High‑dose aspirin: heightened gastrointestinal toxicity. - Selective COX‑2 inhibitors: additive renal and cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors/ARBs: may reduce renal perfusion, especially in volume‑depleted patients. - Diuretics: potential for decreased effectiveness and electrolyte imbalance. - Lithium: ibuprofen may raise serum lithium levels, requiring monitoring.