Nurofen Durance (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Durance, is a non‑steroidal anti‑inflammatory drug presented as a strength/form for oral use. It treats pain, inflammation and fever in adults and children when appropriate.

GNH USA supplies Nurofen Durance as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to relieve several common conditions. - Headache: reduces pain and associated discomfort. - Dental pain: alleviates post‑extraction or procedure soreness. - Musculoskeletal pain: eases aches from strains, sprains and minor arthritis. - Fever: lowers elevated body temperature. - Menstrual cramps: diminishes cramping and pelvic discomfort.

Adverse reactions can range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia or mild abdominal pain. - Headache: transient headache may occur. - Dizziness: occasional light‑headedness. - Rash: mild skin irritation or erythema. - Elevated blood pressure: slight increase in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage. - Renal impairment: reduced kidney function or acute failure. - Severe allergic reaction: anaphylaxis, angioedema or bronchospasm. - Liver injury: hepatitis or elevated liver enzymes. - Cardiovascular events: increased risk of heart attack or stroke.

Before using Nurofen Durance, consider the following safety measures. - Contraindications: avoid if you have a known allergy to ibuprofen or other NSAIDs. - Gastrointestinal risk: use with caution if you have a history of ulcers or bleeding. - Cardiovascular caution: patients with heart disease should consult a physician. - Renal function: monitor kidney health in those with existing renal impairment. - Pregnancy and lactation: discuss risks with a healthcare professional before use. - Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture.

Ibuprofen may interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants: increased risk of bleeding when combined with warfarin or other blood thinners. - High‑dose aspirin: additive gastrointestinal toxicity. - Selective COX‑2 inhibitors: heightened cardiovascular risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors: may reduce antihypertensive effect and affect kidney function. - Diuretics: potential for reduced renal perfusion. - Lithium: ibuprofen can increase lithium serum levels. - Methotrexate: may raise methotrexate toxicity. - SSRIs: combined use can increase bleeding risk.