Nurofen Day & Night Cold & Flu (Phenylephrine Hydrochloride, Ibuprofen Bp)

Ibuprofen and phenylephrine hydrochloride, the active ingredients in Nurofen Day & Night Cold & Flu, are a non‑steroidal anti‑inflammatory drug and a nasal decongestant respectively, presented as oral tablets for oral use. They are formulated to relieve fever, pain, and nasal congestion associated with cold and flu in adults and children over 12 years of age.

GNH USA supplies Nurofen Day & Night Cold & Flu as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Nurofen Day & Night Cold & Flu combines an NSAID and a decongestant to address common cold‑and‑flu symptoms. - Fever: lowers elevated body temperature. - Headache: eases pain associated with sinus pressure. - Nasal congestion: reduces swelling of nasal passages for easier breathing. - Body aches and sore throat: alleviates muscular discomfort and throat irritation. - General flu discomfort: provides overall symptom relief for improved daily functioning.

Common Side Effects: - Stomach upset or dyspepsia. - Nausea or vomiting. - Dizziness or light‑headedness. - Headache. - Mild skin rash. - Dry mouth.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer formation. - Severe allergic reactions such as anaphylaxis. - Liver enzyme elevation or hepatic injury. - Acute kidney injury or reduced renal function. - Severe skin reactions (e.g., Stevens‑Johnson syndrome). - Cardiovascular events such as hypertension or thrombotic episodes.

Before using Nurofen Day & Night Cold & Flu, consider the following precautions: - Assess medical history: avoid if you have active peptic ulcer, severe heart failure, or uncontrolled hypertension. - Review kidney and liver function: use with caution in patients with renal or hepatic impairment. - Monitor for asthma: phenylephrine may exacerbate bronchospasm in susceptible individuals. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Drug interactions: discuss all concurrent medications with a clinician. - Store at ambient temperature: keep below 25°C, retain in original packaging, and protect from moisture.

Nurofen Day & Night Cold & Flu may interact with several medicines. Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - Monoamine oxidase inhibitors (MAOIs): potential hypertensive crisis with phenylephrine. - SSRIs or SNRIs: elevated bleeding risk. - High‑dose antihypertensives: phenylephrine may counteract blood‑pressure control. Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect. - Diuretics: monitor renal function and electrolytes. - Lithium: ibuprofen may increase lithium levels. - Corticosteroids: increased risk of gastrointestinal ulceration. - Beta‑blockers: phenylephrine may diminish therapeutic response.