Nurofen 400 Soditabs (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen 400 Soditabs, is a non‑steroidal anti‑inflammatory drug presented as a 400 mg tablet for oral use. It relieves pain, reduces fever and eases inflammation in adults and children over 12 years of age.

GNH USA supplies Nurofen 400 Soditabs as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to provide symptomatic relief in several common conditions.

- Headache: reduces pain and improves daily functioning - Dental pain: alleviates post‑extraction or procedural discomfort - Musculoskeletal pain: eases aches from strains, sprains and arthritis - Fever: lowers elevated body temperature in acute febrile states - Menstrual cramps: diminishes dysmenorrhoeic pain for many women

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain - Headache: transient worsening before relief - Dizziness or light‑headedness - Skin rash or mild itching - Elevated blood pressure in susceptible individuals

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe allergic reactions such as anaphylaxis - Hepatic or renal impairment with prolonged use - Cardiovascular events including heart attack or stroke - Blood dyscrasias such as thrombocytopenia

Before initiating therapy, consider the following safety measures:

- Assess renal function: patients with chronic kidney disease may need dose adjustment - Evaluate gastrointestinal risk: avoid in individuals with active ulcers or recent GI bleeding - Review cardiovascular history: use cautiously in those with hypertension or heart disease - Check for asthma or NSAID‑sensitive reactions: monitor for bronchospasm - Avoid concurrent use with other NSAIDs or anticoagulants unless directed - Store at below 25°C: keep in the original packaging, protect from moisture and light

Ibuprofen may interact with several medication classes, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk - High‑dose aspirin aspirin   - Selective serotonin reuptake inhibitors (SSRIs) - Lithium   - Corticants 

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