GNH USA

Europe — EMA

Nuralgan (Ibuprofen, Paracetamol)

GNH USA supplies Nuralgan (Ibuprofen/Paracetamol), a combined NSAID and analgesic/antipyretic for pain relief and fever reduction.

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What is Ibuprofen, Paracetamol?

Ibuprofen and Paracetamol, the active ingredients in Nuralgan, are an NSAID and an analgesic/antipyretic presented as an oral dosage form for oral use. They are combined to provide relief from mild to moderate pain and reduce fever in adults and children when appropriate.

GNH USA supplies Nuralgan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen, Paracetamol used for?

Nuralgan combines ibuprofen and paracetamol to act on inflammatory and pain pathways, offering relief for several common conditions. - Mild to moderate pain: reduces discomfort from dental, postoperative or injury‑related pain. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Headache: alleviates tension‑type and mild migraine symptoms. - Musculoskeletal pain: eases aches from strains, sprains or arthritis.

What are the side effects of Ibuprofen, Paracetamol?

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort. - Headache: mild transient headache may occur. - Dizziness: occasional light‑headedness. - Rash: mild skin irritation or erythema. - Elevated liver enzymes: transient increase in laboratory values.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions: anaphylaxis, angioedema. - Hepatotoxicity: marked liver injury, especially with overdose. - Renal impairment: acute kidney injury in susceptible individuals. - Blood disorders: thrombocytopenia or neutropenia.

What precautions apply to Ibuprofen, Paracetamol?

Before using Nuralgan, consider the following precautions: - Assess renal function: avoid in severe renal impairment. - Evaluate hepatic status: use with caution in liver disease. - Review gastrointestinal history: avoid in active ulcer or bleeding. - Monitor for hypersensitivity: discontinue if rash or swelling develops. - Avoid concurrent NSAIDs: increase risk of GI and renal events. - Store at ambient temperature: keep below 25°C, protect from moisture and keep in original packaging.

What does Ibuprofen, Paracetamol interact with?

Nuralgan may interact with several medicines, requiring attention to avoid adverse outcomes. Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity. - Hepatotoxic drugs (e.g., isoniazid, methotrexate): amplified liver injury. Moderate Interactions (Monitor Closely): - ACE inhibitors or diuretics: possible reduction in renal function. - Antihypertensives: ibuprofen may blunt blood pressure control. - Lithium: ibuprofen may raise serum lithium levels.

Frequently asked questions

What is Nuralgan used for?+
Nuralgan is a combination of ibuprofen and paracetamol used to relieve mild to moderate pain and to reduce fever. It is commonly prescribed for conditions such as headaches, musculoskeletal aches, dental pain, and febrile illnesses.
How does ibuprofen/paracetamol work in Nuralgan?+
Ibuprofen blocks cyclooxygenase enzymes, lowering prostaglandin production and reducing inflammation and peripheral pain signals. Paracetamol acts mainly in the central nervous system, inhibiting prostaglandin synthesis and modulating pain pathways, providing antipyretic and analgesic effects.
What is the usual dose of Nuralgan?+
The appropriate dose of Nuralgan is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is Nuralgan safe during pregnancy or breastfeeding?+
Safety of Nuralgan in pregnancy or while breastfeeding should be evaluated by a qualified healthcare provider. Ibuprofen may be avoided in the third trimester, and paracetamol is generally considered safer, but professional guidance is essential.
How do I order Nuralgan from GNH USA?+
To order Nuralgan, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Nuralgan compare with using ibuprofen or paracetamol alone?+
Nuralgan combines the anti‑inflammatory action of ibuprofen with the central analgesic and antipyretic effects of paracetamol, potentially offering broader pain relief and fever control than either agent alone. However, combined therapy may increase the risk of certain side effects, so clinical judgment is required.
How should Nuralgan be stored and handled?+
Nuralgan should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture. Keep the product out of reach of children and avoid exposure to direct sunlight.
How is Nuralgan administered?+
Nuralgan is taken orally, usually with a glass of water. It may be taken with or without food, depending on the prescriber’s advice, to minimize gastrointestinal discomfort.
What are the most serious risks associated with Nuralgan?+
Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, significant liver injury (hepatotoxicity), and acute kidney injury, especially in patients with pre‑existing renal or hepatic disease.
Who should not use Nuralgan?+
Individuals with known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation, those with active gastrointestinal bleeding, severe liver or kidney disease, and patients on anticoagulant therapy without medical supervision should avoid using Nuralgan.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen, Paracetamol
Route
Oral Use
Manufacturer
Laboratoires Smb S.A.
Origin
EU

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