GNH USA

Europe — EMA

Numeta G16% E

GNH USA supplies Numeta G16% E (Amino Acid Mix), a parenteral nutrition supplement for critical care and neonatal patients. Request a quote for global supply.

Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio

Request sourcing

1
Pack/s

What is Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

Valine, the active ingredient in Numeta G16% E, is a parenteral nutrition supplement presented as a 16% concentration for intravenous use. It supports metabolic needs in patients requiring comprehensive amino acid nutrition, particularly in critical care and neonatal settings. GNH USA supplies Numeta G16% E as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and neonatal intensive care units worldwide.

GNH USA supplies Numeta G16% E as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and neonatal intensive care units worldwide.

What is Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio used for?

Numeta G16% E is used as a component of parenteral nutrition regimens for patients with increased protein and amino acid requirements.

- Critical care patients: provides essential amino acids to support catabolic stress response. - Neonates and preterm infants: supplies balanced amino acid profile for growth and development. - Post‑surgical patients: aids in protein synthesis during recovery. - Patients with malabsorption syndromes: delivers nutrition when enteral feeding is insufficient. - Long‑term home parenteral nutrition: maintains nutritional status over extended periods.

What are the side effects of Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

Numeta G16% E may be associated with infusion‑related reactions and metabolic disturbances.

Common Side Effects: - Hyperglycaemia: elevated blood glucose levels during infusion. - Electrolyte imbalance: changes in potassium, sodium or calcium concentrations. - Mild fever or chills: transient temperature rise during administration. - Local irritation: redness or discomfort at the infusion site. - Nausea: occasional sensation of queasiness. - Headache: mild headache reported by some patients.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate medical intervention. - Metabolic acidosis: significant drop in blood pH due to amino acid metabolism. - Hyperosmolarity: increased serum osmolarity leading to fluid shifts. - Thrombophlebitis: inflammation of the vein with clot formation. - Sepsis: infection risk if aseptic technique is compromised. - Renal impairment: worsening kidney function in susceptible individuals.

What precautions apply to Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

When using Numeta G16% E, clinicians should assess patient-specific factors and monitor relevant parameters.

- Assess renal function: evaluate baseline creatinine and adjust infusion rate if needed. - Monitor blood glucose: check glucose levels regularly during therapy. - Check electrolytes: maintain potassium, sodium and calcium within target ranges. - Observe infusion site: watch for signs of phlebitis or infiltration. - Review hepatic function: consider liver enzyme trends in long‑term use. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio interact with?

Numeta G16% E can interact with other intravenously administered agents, influencing metabolic balance and infusion compatibility.

Major Interactions (Avoid): - Incompatible solutions: avoid mixing with calcium‑containing solutions that may precipitate. - High‑dose insulin: concurrent use may exacerbate hypoglycaemia.

Moderate Interactions (Monitor Closely): - Diuretics: may increase electrolyte loss, requiring closer monitoring. - Corticosteroids: can augment protein catabolism, affecting amino‑acid requirements. - Parenteral lipid emulsions: combined regimens need careful osmolarity assessment. - Anticoagulants: monitor clotting parameters if central venous access is used. - Vasopressors: may alter peripheral circulation affecting infusion tolerance.

Frequently asked questions

What is Numeta G16% E used for?+
Numeta G16% E is an intravenous amino‑acid solution used as part of total parenteral nutrition to provide essential and non‑essential amino acids for patients who cannot receive adequate nutrition by mouth or tube, such as critically ill adults, neonates, and individuals on long‑term home parenteral nutrition.
How does the active ingredient Valine work in Numeta G16% E?+
Valine, together with the other amino acids in the formulation, is delivered directly into the bloodstream where it serves as a building block for protein synthesis, supports nitrogen balance, and participates in metabolic pathways that generate energy and neurotransmitters, helping meet the heightened metabolic demands of sick or growing patients.
What is the usual dose of Numeta G16% E?+
The prescribed dose of Numeta G16% E is individualized by the treating clinician based on the patient’s weight, age, metabolic needs and laboratory parameters. Healthcare professionals calculate the appropriate infusion rate and total daily amino‑acid requirement for each patient.
Is Numeta G16% E safe during pregnancy or breastfeeding?+
Safety data for Numeta G16% E in pregnancy and lactation are limited because it is intended for parenteral nutrition in hospitalized settings. Use is generally reserved for situations where the benefits to the mother outweigh potential risks, and it should only be administered under close medical supervision.
How do I order Numeta G16% E from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.
How does Numeta G16% E compare with other parenteral amino‑acid solutions?+
Numeta G16% E offers a 16% amino‑acid concentration with a balanced profile of essential and non‑essential amino acids, making it suitable for both neonatal and adult formulations. Compared with lower‑concentration mixes, it provides a higher amino‑acid load per volume, which can reduce total infusion volume in patients with fluid restrictions.
What are the storage and handling requirements for Numeta G16% E?+
Store Numeta G16% E at ambient temperature, protected from moisture and direct sunlight, in its original sealed container. Avoid freezing and ensure the solution is used within the manufacturer‑specified period after opening.
How is Numeta G16% E administered?+
Numeta G16% E is administered intravenously, typically via a central venous catheter or a peripheral line compatible with the solution’s osmolarity. The infusion rate is set by the prescribing clinician and the solution is added to the total parenteral nutrition bag or infused as a separate amino‑acid module.
What are the most serious risks associated with Numeta G16% E?+
Serious risks include anaphylactic reactions, metabolic acidosis, hyperosmolarity, thrombophlebitis, sepsis from contamination, and renal impairment in susceptible patients. Prompt recognition and management of these events are essential, and patients should be monitored closely during infusion.
Who should not use Numeta E ?+
Numeta G16% E is contraindicated in patients with known hypersensitivity to any of its amino‑acid components, those with severe renal or hepatic failure where amino‑acid clearance is compromised, and individuals in whom an incompatible intravenous solution is required.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio
Route
Intravenous Use
Manufacturer
Baxter Czech Spol. S R.O.
Origin
EU