GNH USA

Europe — EMA

Numeta G13%e

GNH USA supplies Numeta G13%e (amino acid mixture), a parenteral nutrition solution for critical care and postoperative patients.

Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio

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What is Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methionine, the active ingredients in Numeta G13%e, are an amino acid mixture presented as an intravenous solution for parenteral nutrition use. It provides essential and non‑essential amino acids to support protein synthesis in patients requiring nutritional support.

GNH USA supplies Numeta G13%e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

What is Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio used for?

Numeta G13%e is used as a parenteral nutrition amino acid infusion to address protein and nitrogen needs in several clinical situations.

- Severe malnutrition: supplies essential amino acids to restore nitrogen balance. - Post‑operative recovery: supports wound healing and muscle rebuilding after surgery. - Critical illness: provides nutrition when oral intake is impossible or insufficient. - Major burns: meets heightened protein requirements in extensive burn patients.

What are the side effects of Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

Adverse reactions may occur with any intravenous amino acid formulation. Monitoring and appropriate clinical management are essential.

Common Side Effects: - Injection site pain: discomfort at the infusion site. - Phlebitis: inflammation of the vein used for administration. - Hypernatremia: elevated serum sodium levels. - Metabolic alkalosis: shift toward higher blood pH. - Elevated blood urea nitrogen: increased nitrogen waste.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate intervention. - Severe electrolyte imbalance: dangerous shifts in potassium, calcium, or magnesium. - Renal dysfunction: impaired kidney function potentially exacerbated by high nitrogen load. - Hyperammonemia: excess ammonia accumulation, particularly in hepatic impairment.

What precautions apply to Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio?

Careful patient assessment and monitoring are required when using Numeta G13%e. - Renal function assessment: evaluate creatinine clearance before initiation. - Electrolyte monitoring: check serum electrolytes regularly during therapy. - Hepatic impairment adjustment: modify infusion rate in patients with liver disease. - Hypersensitivity screening: avoid in individuals with known allergy to any amino acid component. - Aseptic preparation: use sterile technique to prevent contamination. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio interact with?

Amino acid infusions can interact with other medications and solutions, influencing safety and efficacy.

Major Interactions (Avoid): - High‑dose potassium chloride: may cause dangerous hyperkalemia when combined. - Certain loop diuretics: can exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Concurrent glucose IV solutions: may affect blood glucose control. - Nephrotoxic drugs (e.g., aminoglycosides): require renal function monitoring. - Chelating antibiotics (e.g., tetracyclines): may reduce amino acid availability. - Other parenteral nutrition components: balance total nitrogen and caloric load.

Frequently asked questions

What is Numeta G13%e used for?+
Numeta G13%e is an intravenous amino acid solution used in parenteral nutrition to provide essential and non‑essential amino acids for patients who cannot meet their protein needs through oral or enteral routes, such as those in critical care, post‑operative recovery, severe malnutrition, or extensive burns.
How does the amino acid mixture in Numeta G13%e work?+
The mixture supplies a balanced profile of amino acids that serve as building blocks for protein synthesis, replenish nitrogen stores, and support metabolic processes like tissue repair and immune function. Delivered directly into the bloodstream, it bypasses the digestive system, ensuring rapid availability for patients with compromised gastrointestinal absorption.
What is the usual dose of Numeta G13%e?+
The dose of Numeta G13%e is individualized by the prescribing clinician based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional goals. Healthcare professionals calculate the infusion rate to meet specific protein and nitrogen requirements.
Is Numeta G13%e safe during pregnancy or breastfeeding?+
Use of Numeta G13%e during pregnancy or lactation should be considered only if clearly needed and after evaluating potential benefits versus risks. The prescribing physician should assess maternal and fetal health, as amino acid requirements may differ, and monitor both mother and infant closely.
How do I order Numeta G13%e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required), and necessary import documentation.
How does Numeta G13%e compare with other parenteral amino acid products?+
Numeta G13%e offers a comprehensive blend of essential and non‑essential amino acids in a formulation designed for balanced nitrogen delivery. Compared with older single‑amino‑acid solutions, it reduces the need for multiple infusions and helps maintain a more physiological amino acid profile, potentially improving metabolic stability and patient outcomes.
What are the storage and handling requirements for Numeta G13%e?+
The product must be stored refrigerated at 2‑8 °C, protected from light, and never frozen. Before use, inspect the vial for any particulate matter or discoloration, and allow it to reach room temperature if required by the administration protocol, following aseptic handling procedures.
How is Numeta G13%e administered?+
Numeta G13%e is administered intravenously, typically via a peripheral or central venous catheter. The infusion rate is set according to the clinician’s prescription, and the solution is diluted in compatible IV fluids as directed. Continuous monitoring of vital signs and laboratory parameters is recommended during the infusion.
What are the most serious risks associated with Numeta G13%e?+
Serious risks include anaphylactic reactions, severe electrolyte imbalances (such as hyperkalemia or hypernatremia), renal dysfunction, and hyperammonemia, especially in patients with liver impairment. Prompt recognition and management of these events are essential, and patients should be closely monitored throughout therapy.
Who should not receive Numeta G13%e?+
Numeta G13%e should be avoided in individuals with known hypersensitivity to any of its amino acid components, in patients with uncontrolled severe electrolyte disturbances, and in those with acute hepatic failure where amino acid metabolism is markedly impaired. Clinical judgment is required for each case.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio
Route
Intravenous Use
Manufacturer
Baxter, S.L.
Origin
EU