Nujol (Liquid Paraffin)

Liquid Paraffin, the active ingredient in Nujol, is a mineral oil laxative presented as a liquid for oral use. It provides lubrication of the intestinal tract to relieve occasional constipation in adults and children.

GNH USA supplies Nujol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nujol (liquid paraffin) is used as a lubricant laxative to manage constipation and related gastrointestinal needs.

- Constipation: softens stool and facilitates easy passage in adults and children. - Bowel preparation for radiographic studies: provides gentle cleansing of the colon before imaging procedures. - Prevention of anal fissure discomfort: reduces friction during defecation, helping to alleviate pain associated with fissures.

Liquid paraffin may cause a range of adverse reactions, most of which are mild and related to its oily nature.

Common Side Effects: - Abdominal cramping or discomfort. - Oily or greasy stools. - Nausea or mild vomiting. - Flatulence or bloating. - Diarrhea or loose stools. - Rectal leakage of oil.

Serious or Rare Side Effects: - Aspiration pneumonia if the product is inhaled. - Lipid pneumonia from chronic aspiration. - Severe allergic reaction (rash, swelling, anaphylaxis). - Persistent abdominal pain. - Intestinal obstruction. - Electrolyte imbalance with prolonged use.

When prescribing or using Nujol, consider the following safety measures.

- Assess for bowel obstruction: avoid use if obstruction is suspected. - Use with caution in patients with dysphagia: risk of aspiration. - Avoid in individuals with known oil intolerance or hypersensitivity. - Monitor for signs of aspiration, especially in bedridden patients. - Do not use during acute abdominal pain without medical evaluation. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

Liquid paraffin can affect the absorption of several concomitant medications and nutrients.

Major Interactions (Avoid): - Fat‑soluble vitamins (A, D, E, K): reduced absorption leading to deficiency. - Warfarin, digoxin, levothyroxine: decreased oral bioavailability. - Concurrent use with other laxatives: risk of electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Antacids: may delay gastric emptying and alter drug onset. - Tetracycline antibiotics: reduced efficacy due to binding with oil. - Cholesterol‑lowering agents (e.g., statins): possible alteration in absorption.