Europe — EMA
Nozinan (Levomepromazine Maleate)
Levomepromazine, the active ingredient in Nozinan, is a phenphen presented as a strength/form for oral use. It is employed in the management of severe agitation, nausea, and psychotic disorders, particularly in…
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What is Levomepromazine Maleate?
Levomepromazine, the active ingredient in Nozinan, is a phenphen presented as a strength/form for oral use. It is employed in the management of severe agitation, nausea, and psychotic disorders, particularly in palliative care settings. GNH USA supplies Nozinan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
GNH USA supplies Nozinan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
What is Levomepromazine Maleate used for?
Levomepromazine is a low‑potency phenothiazine antipsychotic that acts on multiple neurotransmitter pathways, especially dopamine and serotonin receptors.
- Severe agitation in palliative care: helps control distressing restlessness and anxiety. - Nausea and vomiting: provides relief when other anti‑emetics are insufficient. - Psychotic disorders: reduces hallucinations and delusions in schizophrenia and related conditions.
What are the side effects of Levomepromazine Maleate?
Levomepromazine may cause a range of adverse reactions, varying from mild to severe.
Common Side Effects: - Drowsiness: patients often feel sleepy. - Dry mouth: reduced salivation is frequent. - Constipation: slowed gastrointestinal motility. - Orthostatic hypotension: drop in blood pressure on standing. - Blurred vision: visual accommodation may be affected. - Weight gain: increased appetite can lead to weight increase.
Serious or Rare Side Effects: - Neuroleptic malignant syndrome: a life‑threatening reaction with fever and muscle rigidity. - Tardive dyskinesia: persistent involuntary movements. - Severe hypotension: marked drop in blood pressure. - Cardiac arrhythmias: irregular heart rhythms. - Agranulocytosis: dangerously low white‑blood‑cell count. - Hepatic dysfunction: liver enzyme elevations.
What precautions apply to Levomepromazine Maleate?
When prescribing Levov…
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