Noxtor (Ketotifen Hydrogen Fumarate)

Ketotifen Hydrogen Fumarate, the active ingredient in Noxtor, is an antihistamine presented as a tablet for oral use. It is used to manage allergic conditions such as seasonal allergic rhinitis and chronic urticaria in adults and children. GNH USA supplies Noxtor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Noxtor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketotifen is an antihistamine that works on mast‑cell mediated allergic pathways. It is indicated for several allergic disorders: - Seasonal allergic rhinitis: reduces nasal congestion, itching and sneezing. - Chronic idiopathic urticaria: decreases the frequency and severity of hives. - Allergic conjunctivitis: alleviates eye itching and redness. - Atopic dermatitis (adjunct therapy): helps control pruritus when used with topical treatments. - Exercise‑induced bronchospasm prophylaxis: lessens airway narrowing during physical activity.

Ketotifen may cause a range of adverse reactions.

Common Side Effects: - Drowsiness: mild to moderate sedation, especially after the first doses. - Dry mouth: reduced salivary flow causing a sticky feeling. - Weight gain: modest increase in body weight over prolonged use. - Gastrointestinal discomfort: nausea or mild abdominal cramps. - Headache: transient tension‑type headache.

Serious or Rare Side Effects: - Hepatotoxicity: abnormal liver enzymes indicating possible liver injury. - Hematologic abnormalities: eosinophilia or neutropenia. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiac arrhythmias: rare cases of palpitations or irregular heartbeat. - Anaphylaxis: immediate hypersensitivity requiring emergency care.

When prescribing Ketotifen, clinicians should consider several safety aspects: - Pregnancy: limited data; use only if the potential benefit justifies the potential risk. - Breastfeeding: excreted in milk; weigh benefits to the infant against maternal need. - Hepatic impairment: dose adjustment may be required; monitor liver function. - Concomitant CNS depressants: may enhance drowsiness; advise caution with alcohol or sedatives. - Driving and machinery: patients should be warned about possible sedation. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Ketotifen can interact with other medicines, altering its effectiveness or safety profile.

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