GNH USA

Europe — EMA

Novaminsulfon Lichtenstein (Metamizole Sodium Monohydrate)

GNH USA supplies Novaminsulfon Lichtenstein (Metamizole Sodium), a non‑opioid analgesic for pain and fever. Request a quote for global supply today.

Metamizole Sodium Monohydrate

Request sourcing

1
Pack/s

What is Metamizole Sodium Monohydrate?

Metamizole Sodium, the active ingredient in Novaminsulfon Lichtenstein, is a pyrazolone (non‑opioid analgesic) presented as an oral formulation for systemic use. It is employed to relieve moderate to severe pain and to reduce fever in adult patients, and is indicated for short‑term management of acute pain and febrile states.

GNH USA supplies Novaminsulfon Lichtenstein as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across European and global markets.

What is Metamizole Sodium Monohydrate used for?

Novaminsulfon Lichtenstein (metamizole sodium) is used in the analgesic and antipyretic pathway to manage pain and fever.

Acute Pain: provides rapid analgesic relief for short‑term severe pain. Post‑operative Pain: helps control discomfort following surgical procedures. High Fever: reduces elevated body temperature when other antipyretics are insufficient. Cancer‑related Pain: offers additional analgesia for breakthrough pain in oncology patients.

What are the side effects of Metamizole Sodium Monohydrate?

Metamizole sodium may cause a range of adverse reactions, varying from mild to potentially life‑threatening.

Common Side Effects: - Nausea - Vomiting - Dizziness - Skin rash

Serious or Rare Side Effects: - Agranulocytosis (severe reduction of white blood cells) - Anaphylactic or severe allergic reactions - Stevens‑Johnson syndrome or other severe cutaneous adverse reactions

What precautions apply to Metamizole Sodium Monohydrate?

When prescribing Novaminsulfon Lichtenstein, clinicians should consider several safety measures.

Assess renal function: adjust use in patients with impaired kidney function. Monitor blood counts: regular hematologic monitoring is recommended during therapy. Avoid in known hypersensitivity: discontinue if an allergic reaction occurs. Use caution with hepatic impairment: consider liver function before prescribing. Do not combine with other pyrazolones or NSAIDs without medical supervision. Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Metamizole Sodium Monohydrate interact with?

Metamizole sodium can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Concurrent use with other NSAIDs may increase risk of agranulocytosis. - Co‑administration with anticoagulants may enhance bleeding tendency.

Moderate Interactions (Monitor Closely): - Combined with antihypertensive agents may potentiate hypotensive effects. - Interaction with cytotoxic chemotherapy may exacerbate bone‑marrow suppression. - Alcohol consumption may increase gastrointestinal irritation.

Frequently asked questions

What is Novaminsulfon Lichtenstein used for?+
Novaminsulfon Lichtenstein contains metamizole sodium, which is indicated for the short‑term relief of moderate to severe pain and for the reduction of high fever when other treatments are insufficient. It is commonly used in acute pain scenarios, postoperative settings, and in patients requiring antipyretic therapy.
How does Metamizole Sodium work to relieve pain and fever?+
Metamizole sodium works by non‑selectively inhibiting cyclooxygenase enzymes, leading to decreased prostaglandin production. Lower prostaglandin levels reduce peripheral pain signaling and central sensitization, while also acting on the hypothalamic thermoregulatory center to lower elevated body temperature.
What is the usual dose of Novaminsulfon Lichtenstein?+
The appropriate dose of Novaminsulfon Lichtenstein is determined by the prescribing healthcare professional based on the individual patient's condition, severity of symptoms, age, renal and hepatic function, and other concurrent medications. Patients should follow the prescriber's instructions and not adjust the dose on their own.
Is Novaminsulfon Lichtenstein safe during pregnancy or breastfeeding?+
Safety data for metamizole sodium in pregnancy and lactation are limited. It should only be used during pregnancy or while breastfeeding if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers must evaluate the risk‑benefit profile for each individual case.
How do I order Novaminsulfon Lichtenstein from GNH USA?+
To order Novaminsulfon Lichtenstein, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials. The team then replies with pricing, availability, shipping details and any required import documentation.
How does Novaminsulfon Lichtenstein compare with other analgesics?+
Novaminsulfon Lichtenstein (metamizole) is a non‑opioid pyrazolone analgesic, offering strong analgesic and antipyretic effects without the gastrointestinal irritation typical of many NSAIDs. Unlike opioids, it does not cause respiratory depression, but it carries a risk of rare blood dyscrasias such as agranulocytosis, which must be monitored.
What are the storage and handling requirements for Novaminsulfon Lichtenstein?+
Novaminsulfon Lichtenstein should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid exposure to extreme temperatures or humidity.
How is Novaminsulfon Lichtenstein administered?+
Novaminsulfon Lichtenstein is administered orally, as directed by a qualified healthcare professional. The tablet or oral formulation should be swallowed with water, and the exact administration schedule should follow the prescriber's instructions.
What are the most serious risks to watch for when using Metamizole Sodium?+
The most serious risks associated with metamizole sodium include agranulocytosis, a potentially fatal reduction in white blood cells, and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be instructed to seek immediate medical attention if they experience signs of infection, rash, or breathing difficulties.
Who should not use Novaminsulfon Lichtenstein?+
Novaminsulfon Lichtenstein should be avoided in individuals with known hypersensitivity to metamizole or other pyrazolones, in patients with pre‑existing severe bone‑marrow disorders, and in those with uncontrolled hepatic or renal impairment unless closely monitored. It is also contraindicated in patients receiving other pyrazolone‑containing medications.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Metamizole Sodium Monohydrate
Route
Oral Use
Manufacturer
Winthrop Arzneimittel Gmbh
Origin
EU

Related products

Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Algiotop

Algiotop

Metamizole Sodium Monohydrate

S.C. Santa S.A.
EU
Algocalmin

Algocalmin

Metamizole Sodium Monohydrate

Zentiva S.A.
EU