GNH USA

Europe — EMA

Novalgin (Metamizole Sodium Monohydrate)

GNH USA supplies Novalgin (Metamizole Sodium), a pyrazolone analgesic for pain and fever, for hospitals and pharmacies. Request a quote for global supply.

Metamizole Sodium Monohydrate

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What is Metamizole Sodium Monohydrate?

Metamizole Sodium, the active ingredient in Novalgin, is a pyrazolone analgesic presented as an oral formulation for oral use. It treats pain and fever in adults.

GNH USA supplies Novalgin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Sodium Monohydrate used for?

Metamizole Sodium is a pyrazolone analgesic used to manage pain and fever.

Pain: provides effective analgesia for moderate to severe pain Fever: reduces elevated body temperature in febrile conditions Postoperative pain: helps control pain after surgical procedures Visceral colic: alleviates spasm-related abdominal discomfort

What are the side effects of Metamizole Sodium Monohydrate?

Metamizole Sodium may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea - Vomiting - Dizziness - Headache - Mild skin rash - Low blood pressure

Serious or Rare Side Effects: - Agranulocytosis (severe drop in white blood cells) - Severe allergic reactions such as anaphylaxis - Blood dyscrasias including thrombocytopenia - Hepatic dysfunction - Renal impairment - Stevens‑Johnson syndrome

What precautions apply to Metamizole Sodium Monohydrate?

Before prescribing Metamizole Sodium, consider the following precautions to ensure safe use.

Assess blood counts: Perform baseline and periodic complete blood count monitoring Use with caution in renal or hepatic impairment: Adjust dose or avoid if severe dysfunction Avoid in known hypersensitivity: Do not prescribe to patients with previous allergic reactions to pyrazolones Monitor for signs of infection: Promptly evaluate fever or sore throat indicating possible agranulocytosis Do not use in children unless specifically indicated: Pediatric use requires careful risk assessment Store at ambient temperature: keep in the original pack, protect from moisture

What does Metamizole Sodium Monohydrate interact with?

Metamizole Sodium can interact with other medicines; some interactions require avoidance while others need close monitoring.

Major Interactions (Avoid): - Concurrent use with other myelotoxic agents (e.g., chemotherapy) may increase risk of severe blood disorders - Combination with anticoagulants (e.g., warfarin) can enhance bleeding risk - Co‑administration with other NSAIDs or COX inhibitors raises the chance of agranulocytosis and gastrointestinal toxicity

Moderate Interactions (Monitor Closely): - ACE inhibitors may potentiate hypotensive effects - Diuretics can exacerbate electrolyte disturbances - Alcohol may increase central nervous system depression - Certain antiepileptic drugs may alter Metamizole metabolism

Frequently asked questions

What is Novalgin used for?+
Novalgin contains Metamizole Sodium, a pyrazolone analgesic prescribed for the relief of moderate to severe pain and for the reduction of high fever when other treatments are insufficient. It is used in adult patients in various clinical settings, such as postoperative pain, acute musculoskeletal pain, and febrile conditions.
How does Metamizole Sodium work?+
Metamizole Sodium exerts its effect by non‑selectively inhibiting cyclooxygenase enzymes, which reduces the synthesis of prostaglandins involved in pain signaling and fever generation. Additionally, it has central analgesic activity and a spasmolytic effect that helps relieve visceral pain.
What is the usual dose of Novalgin?+
The dosage of Novalgin is determined by the prescribing physician based on the patient’s condition, age, weight, and response to therapy. The prescriber will select the appropriate strength, frequency, and duration in accordance with local clinical guidelines and regulatory requirements.
Is Novalgin safe during pregnancy or breastfeeding?+
Safety of Metamizole Sodium in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional after careful assessment.
How do I order Novalgin from GNH USA?+
To place an order, submit an enquiry on the Novalgin product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Novalgin compare with other analgesics?+
Compared with traditional NSAIDs, Metamizole Sodium offers potent analgesic and antipyretic effects with a lower incidence of gastrointestinal irritation, but it carries a unique risk of agranulocytosis. Unlike opioids, it does not produce significant respiratory depression, making it a useful alternative for certain pain indications when monitored appropriately.
How should Novalgin be stored?+
Novalgin should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in areas with high humidity or temperature fluctuations.
How is Novalgin administered?+
Novalgin is administered orally, typically as a tablet or oral solution, and should be taken with or without food as directed by the prescriber. The exact method of administration, including whether to swallow whole or dissolve, depends on the specific dosage form supplied.
What are the most serious risks associated with Novalgin?+
The most serious adverse reactions include agranulocytosis, which can lead to severe infections, and life‑threatening allergic responses such as anaphylaxis. Patients should be monitored for signs of infection, unexplained fever, sore throat, or skin reactions, and immediate medical attention is required if these occur.
Who should not use Novalgin?+
Novalgin should be avoided in individuals with known hypersensitivity to Metamizole or other pyrazolones, in patients with pre‑existing severe blood dyscrasias, and in those for whom safer alternatives are available, such as pregnant women unless absolutely necessary. It is also contraindicated in children unless specifically prescribed by a specialist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metamizole Sodium Monohydrate
Route
Oral Use
Manufacturer
Opella Healthcare Czech S.R.O
Origin
EU

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