GNH USA

Europe — EMA

Noskapin Orifarm Healthcare (Noscapine Hydrochloride)

GNH USA supplies Noskapin (Noscapine Hydrochloride), a antitussive for non‑productive and dry cough relief. Request a quote for global supply.

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What is Noscapine Hydrochloride?

Noscapine Hydrochloride, the active ingredient in Noskapin Orifarm Healthcare, is an antitussive presented as an oral dosage form for oral use. Originating from the European Union market, this over‑the‑counter product suppresses non‑productive coughs in adults and children by acting centrally on the cough reflex, offering symptomatic relief without significant sedation.

GNH USA supplies Noskapin Orifarm Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. All batches meet EU pharmacopeial specifications and are shipped under controlled conditions to ensure product integrity.

What is Noscapine Hydrochloride used for?

Noskapin (noscapine hydrochloride) is an antitussive that acts on the central cough pathway. - Non‑productive cough: reduces cough frequency and intensity in patients with dry cough. - Cough due to upper respiratory tract infection: provides symptomatic relief during viral colds. - Cough associated with bronchitis: helps alleviate persistent dry cough in acute bronchitis.

What are the side effects of Noscapine Hydrochloride?

Noskapin may cause adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea - Dizziness - Headache - Dry mouth

Serious or Rare Side Effects: - Allergic reactions (rash, urticaria, angioedema) - Hepatotoxicity (elevated liver enzymes).

What precautions apply to Noscapine Hydrochloride?

Before using Noskapin, consider the following precautions. - Pregnancy: safety not established; use only if clearly needed. - Breastfeeding: unknown; weigh potential risks against benefits. - Renal impairment: no dosage adjustment required, but monitor severe cases. - Hepatic impairment: use with caution and monitor liver function. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Noscapine Hydrochloride interact with?

Noskapin can interact with other medicines; review the following categories.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of additive central nervous system effects. - CNS depressants (e.g., opioids, benzodiazepines): may enhance sedation.

Moderate Interactions (Monitor Closely): - Alcohol: may increase dizziness. - CYP450 substrates: noscapine may inhibit certain enzymes; monitor plasma levels. - Anticholinergic agents: may exacerbate dry mouth.

Frequently asked questions

What is Noskapin used for?+
Noskapin contains noscapine hydrochloride, an antitussive indicated for the symptomatic relief of non‑productive (dry) coughs, including coughs associated with upper respiratory tract infections and acute bronchitis.
How does noscapine work?+
Noscapine acts centrally by modulating sigma‑1 receptors in the brainstem, which dampens the neural pathways that trigger the cough reflex, thereby reducing the frequency and intensity of coughing without significant sedation.
What is the usual dose of Noskapin?+
The appropriate dose of Noskapin is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Patients should follow the prescriber’s instructions and the product label.
Is Noskapin safe during pregnancy or breastfeeding?+
Safety data for noscapine hydrochloride in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.
How do I order Noskapin from GNH USA?+
To order Noskapin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Noskapin compare with other cough suppressants?+
Compared with opioid‑based suppressants such as codeine, noscapine offers cough relief without the risk of dependence or significant respiratory depression. Unlike dextromethorphan, it has a distinct central mechanism involving sigma‑1 receptors, which may result in a different side‑effect profile.
How should Noskapin be stored and handled?+
Store Noskapin at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability.
How is Noskapin administered?+
Noskapin is administered orally. The tablet or capsule (form not specified) should be swallowed with water, following the dosage instructions provided by the prescriber or printed on the label.
What are the most serious risks associated with Noskapin?+
Serious but rare risks include allergic reactions such as rash, urticaria, angioedema, and potential hepatotoxicity manifested by elevated liver enzymes. Patients should seek immediate medical attention if they experience signs of an allergic response or liver dysfunction.
Who should not use Noskapin?+
Noskapin should be avoided in individuals with known hypersensitivity to noscapine or any excipients, and in patients who have experienced severe allergic reactions to similar antitussive agents. Caution is advised for those with significant liver disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Noscapine Hydrochloride
Route
Oral Use
Manufacturer
Orifarm Healthcare A/S
Origin
EU

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