GNH USA

Europe — EMA

Noscapine Hydrochloride Aurobindo

GNH USA supplies Noscapine Hydrochloride Aurobindo (Noscapine), a antitussive for acute, chronic and infection‑related cough.

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What is Noscapine Hydrochloride?

Noscapine Hydrochloride, the active ingredient in Noscapine Hydrochloride Aurobindo, is an antitussive presented as an oral tablet for oral use. It is employed to suppress cough in adults and children when a non‑opioid cough suppressant is required, and conforms to EU pharmacopeial specifications.

GNH USA supplies Noscapine Hydrochloride Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Noscapine Hydrochloride used for?

Noscapine Hydrochloride is an antitussive that acts on the central cough reflex pathway. - Acute cough: reduces the frequency and intensity of sudden coughing episodes. - Chronic cough: helps control persistent coughing that lasts for weeks. - Cough associated with respiratory infections: alleviates irritation‑driven cough during viral or bacterial upper‑respiratory tract infections.

What are the side effects of Noscapine Hydrochloride?

Adverse reactions to Noscapine Hydrochloride are generally mild, but monitoring is advised.

Common Side Effects: - Nausea: mild stomach upset. - Dizziness: transient light‑headedness. - Fatigue: feeling unusually tired. - Headache: mild to moderate pain. - Gastrointestinal discomfort: mild abdominal cramping. - Rash: mild skin irritation.

Serious or Rare Side Effects: - Allergic reaction: swelling, hives, or difficulty breathing. - Hepatic dysfunction: elevated liver enzymes. - Hematologic changes: unexplained bruising or bleeding. - Severe dizziness: persistent vertigo. - Cardiac arrhythmia: irregular heartbeat. - Anaphylaxis: rapid onset of severe allergic symptoms.

What precautions apply to Noscapine Hydrochloride?

Before using Noscapine Hydrochloride, consider the following safety measures. - Pregnancy: consult a healthcare professional; safety data are limited. - Breastfeeding: discuss potential risks with a physician. - Liver disease: use with caution; monitor hepatic function. - Renal impairment: dose adjustment may be required. - Concomitant CNS depressants: monitor for additive sedation. - Store at ambient temperature: keep below 25°C, protect from moisture and direct sunlight.

What does Noscapine Hydrochloride interact with?

Noscapine Hydrochloride may interact with other medicines; review the following categories.

Major Interactions (Avoid): - MAO inhibitors: risk of enhanced central nervous system effects. - Opioid cough suppressants: potential additive sedation.

Moderate Interactions (Monitor Closely): - Antihistamines: may increase drowsiness. - Benzodiazepines: monitor for excessive sedation. - Alcohol: can potentiate CNS depression. - CYP450 substrates: possible alteration of metabolism. - Herbal supplements (e.g., St. John’s wort): may affect drug levels.

Frequently asked questions

What is Noscapine Hydrochloride Aurobindo used for?+
Noscapine Hydrochloride Aurobindo is used as an antitussive to suppress coughing associated with acute, chronic, or infection‑related respiratory conditions. It provides a non‑opioid option for managing cough in both adults and children.
How does Noscapine Hydrochloride work?+
The compound acts centrally on the medullary cough center, modulating neuronal excitability and inhibiting the transmission of cough‑inducing signals. Although the precise receptor interaction is not fully defined, this central action reduces the cough reflex without significant opioid‑type effects.
What is the usual dose of Noscapine Hydrochloride?+
Dosage is individualized by the prescribing clinician based on the patient’s age, weight, severity of cough, and overall health status. The prescriber determines the appropriate strength, frequency, and duration of therapy.
Is Noscapine Hydrochloride safe during pregnancy or breastfeeding?+
Safety data for use in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing individuals.
How do I order Noscapine Hydrochloride Aurobindo from GNH USA?+
Enquiries can be submitted via the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Noscapine compare with other cough suppressants?+
Noscapine is a non‑opioid antitussive, offering cough relief without the risk of respiratory depression associated with opioid‑based agents such as codeine. It is generally well‑tolerated, though its exact efficacy may vary compared with newer centrally acting agents.
What are the storage and handling requirements for Noscapine Hydrochloride?+
Store the oral tablets at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Noscapine Hydrochloride administered?+
The medication is taken orally, usually with a glass of water. The exact administration schedule—including dose amount and frequency—should follow the prescribing clinician’s instructions.
What are the most serious risks associated with Noscapine Hydrochloride?+
Serious adverse events, though rare, can include severe allergic reactions (anaphylaxis), hepatic dysfunction, and significant cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as swelling, difficulty breathing, jaundice, or irregular heartbeat.
Who should not use Noscapine Hydrochloride?+
Individuals with known hypersensitivity to noscapine or any excipients, patients with severe hepatic impairment, and those taking contraindicated medications (e.g., MAO inhibitors) should avoid this product unless advised otherwise by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Noscapine Hydrochloride
Route
Oral Use
Manufacturer
Aurobindo Pharma B.V.
Origin
EU

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