Noscapine Hcl Teva (Noscapine Hydrochloride)

Noscapine Hydrochloride, the active ingredient in Noscapine Hcl Teva, is an antitussive presented as an oral dosage form for oral use. It suppresses cough in patients requiring symptomatic relief.

GNH USA supplies Noscapine Hcl Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Noscapine Hydrochloride is used as an antitussive to manage cough.

- Acute cough: reduces the frequency and intensity of non‑productive cough episodes. - Chronic cough: provides symptomatic control of persistent cough when other causes have been excluded. - Cough associated with upper respiratory infections: offers relief of irritation‑driven cough without affecting mucus clearance.

Adverse reactions to Noscapine Hydrochloride are generally mild, but clinicians should remain vigilant for both common and serious events.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Dizziness: transient light‑headedness. - Drowsiness: increased sleepiness, especially at higher doses. - Headache: mild cranial discomfort. - Dry mouth: reduced salivation. - Gastrointestinal discomfort: abdominal cramping or mild diarrhea.

Serious or Rare Side Effects: - Allergic reactions: rash, pruritus, or angioedema. - Severe hypotension: sudden drop in blood pressure. - Hepatic enzyme elevation: abnormal liver function tests. - Hematologic abnormalities: neutropenia or thrombocytopenia. - Seizures: rare central nervous system events.

When prescribing Noscapine Hydrochloride, consider the following safety measures.

- Evaluate underlying cause: ensure cough is not a sign of a serious respiratory condition. - Hypersensitivity: avoid in patients with known allergy to noscapine or related compounds. - Hepatic impairment: use with caution in patients with liver disease. - Sedation risk: monitor patients who may be prone to drowsiness or dizziness. - Concomitant CNS depressants: avoid or adjust dose when used with other sedating agents. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Noscapine Hydrochloride may interact with other medicines; awareness of the interaction level helps guide clinical decisions.

Major Interactions (Avoid): - Strong CNS depressants (e.g., opioids, benzodiazepines): additive sedation and respiratory depression. - Other antitussives (e.g., dextromethorphan): risk of excessive cough suppression.

Moderate Interactions (Monitor Closely): - Antihistamines: may increase drowsiness. - Alcohol: can enhance central nervous system effects. - CYP3A4 substrates: noscapine is metabolised by CYP3A4 and may alter plasma levels of co‑administered drugs. - Anticoagulants: monitor INR if used concurrently.