Europe — EMA
Noscaflex Expectorans (Noscapine Hydrochloride, Guaifenesin)
GNH USA supplies Noscaflex Expectorans (Noscapine Hydrochloride, Guaifenesin), a cough suppressant and expectorant for cough. Request a quote for supply.
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What is Noscapine Hydrochloride, Guaifenesin?
Noscapine Hydrochloride, the active ingredient in Noscaflex Expectorans, is an antitussive presented as an oral formulation for oral use. It suppresses the cough centre in the medulla and, together with guaifenesin, helps relieve cough, chest congestion and facilitates mucus clearance in adults and children.
GNH USA supplies Noscaflex Expectorans as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Noscapine Hydrochloride, Guaifenesin used for?
Noscaflex Expectorans, containing an antitussive and an expectorant, is used to manage cough‑related conditions.
- Cough: reduces the frequency and intensity of acute or chronic cough. - Chest congestion: loosens thick bronchial secretions to improve airflow. - Mucus clearance: enhances the volume and fluidity of sputum, making expectoration easier.
What are the side effects of Noscapine Hydrochloride, Guaifenesin?
Common Side Effects: - Nausea: mild stomach upset that may resolve with continued use. - Dizziness: transient light‑headedness, especially when standing quickly. - Headache: mild to moderate pain, often relieved with simple analgesics. - Gastrointestinal discomfort: mild abdominal cramping or loose stools.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylaxis: rapid onset of airway obstruction, hypotension, and shock.
What precautions apply to Noscapine Hydrochloride, Guaifenesin?
Before using Noscaflex Expectorans, consider the following precautions: - Hypersensitivity: avoid if known allergy to noscapine, guaifenesin, or any excipients. - Pediatric use: follow prescriber guidance; dosage may differ for children. - Hepatic impairment: use with caution; monitor liver function if indicated. - Persistent cough: evaluate for underlying conditions such as asthma or infection before long‑term use. - Concomitant CNS depressants: monitor for additive sedation. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Noscapine Hydrochloride, Guaifenesin interact with?
Noscaflex Expectorans may interact with other medicines as follows:
Major Interactions (Avoid): - Other central nervous system depressants (e.g., opioids, benzodiazepines): risk of excessive sedation or respiratory depression. - Monoamine oxidase inhibitors (MAOIs): potential for hypertensive reactions.
Moderate Interactions (Monitor Closely): - Antihistamines: may increase anticholinergic load, leading to dry mouth or constipation. - Bronchodilators (e.g., albuterol): additive effect on airway secretions, requiring dose adjustment. - Warfarin: possible alteration of INR; monitor coagulation parameters regularly.

