GNH USA

Europe — EMA

Norvasc (Amlodipine)

GNH USA supplies Norvasc (Amlodipine), a calcium channel blocker for hypertension and chronic stable angina. Request a quote for global supply today.

Amlodipine

Request sourcing

1
Pack/s

What is Amlodipine?

Amlodipine, the active ingredient in Norvasc, is a calcium channel blocker presented as an oral tablet for oral use. It treats hypertension and chronic stable angina in adults.

GNH USA supplies Norvasc as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Amlodipine used for?

Norvasc is a calcium channel blocker used to manage vascular conditions.

Hypertension: lowers elevated blood pressure to reduce cardiovascular risk. Chronic stable angina: improves chest pain control by increasing coronary blood flow.

What are the side effects of Amlodipine?

Common side effects are generally mild and may resolve with continued therapy.

Common Side Effects: - Headache - Flushing - Peripheral edema - Dizziness - Fatigue - Palpitations

Serious or Rare Side Effects: - Severe hypotension - Myocardial infarction - Hepatic injury - Anaphylactic or severe allergic reactions - Arrhythmias - Angioedema

What precautions apply to Amlodipine?

Before initiating therapy, consider the following precautions. - Blood pressure monitoring: regularly assess to avoid excessive hypotension. - Hepatic impairment: use with caution and adjust dose if needed. - Concomitant antihypertensives: monitor for additive blood pressure lowering effects. - Discontinuation: avoid abrupt cessation to prevent rebound hypertension. - Pregnancy and lactation: evaluate risk‑benefit ratio with a healthcare professional. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Amlodipine interact with?

Amlodipine may interact with several drug classes; review patient medication lists.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase amlodipine levels. - Simvastatin >20 mg: risk of increased statin exposure and myopathy. - Grapefruit juice: can raise plasma concentrations.

Moderate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce efficacy. - Beta‑blockers: additive effect on heart rate and blood pressure. - Diuretics: enhanced antihypertensive effect, monitor electrolytes.

Frequently asked questions

What is Norvasc used for?+
Norvasc (amlodipine) is prescribed to lower high blood pressure (hypertension) and to relieve chest pain caused by chronic stable angina. It helps reduce the workload on the heart and improves blood flow to the heart muscle.
How does amlodipine work?+
Amlodipine blocks L-type calcium channels in the smooth muscle of arteries and the heart. This action prevents calcium from entering cells, causing the blood vessels to relax and widen, which lowers peripheral resistance and reduces blood pressure while also decreasing the heart's oxygen demand.
What is the usual dose of Norvasc?+
The appropriate dose is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other medications. Dosage adjustments are made to achieve optimal blood pressure control or angina relief.
Is Norvasc safe during pregnancy or breastfeeding?+
Safety data are limited. Norvasc should only be used during pregnancy or lactation if the potential benefits justify the possible risks. Patients should discuss their specific situation with a qualified healthcare provider.
How do I order Norvasc from GNH USA?+
To place an order, submit an enquiry on the Norvasc product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Norvasc compare with other antihypertensive drugs?+
Norvasc belongs to the dihydropyridine class of calcium channel blockers, which primarily cause arterial vasodilation. Compared with ACE inhibitors or beta‑blockers, amlodipine has a longer half‑life, a once‑daily dosing schedule, and a lower incidence of cough but may cause peripheral edema more frequently.
How should Norvasc be stored and handled?+
Store Norvasc tablets at room temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from moisture and direct sunlight, and keep out of reach of children.
How is Norvasc administered?+
Norvasc is taken orally, usually once daily, with or without food. Swallow the tablet whole with a full glass of water; do not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.
What are the most serious risks associated with Norvasc?+
Serious adverse reactions, although rare, include severe hypotension, myocardial infarction, significant liver injury, life‑threatening allergic reactions such as anaphylaxis, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as fainting, chest pain, or swelling of the face and throat.
Who should not use Norvasc?+
Norvasc should be avoided in individuals with known hypersensitivity to amlodipine or any component of the formulation, in patients with cardiogenic shock, severe aortic stenosis, or uncontrolled heart failure, and in those who are taking contraindicated medications that may cause dangerous interactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Amlodipine
Route
Oral Use
Manufacturer
Upjohn Eesv
Origin
EU

Related products

Abesyl

Abesyl

Amlodipine

Medochemie Hellas Sa
EU
Adipine

Adipine

Amlodipine

Bausch Health Ireland Limited
EU
Adipine

Adipine

Amlodipine

Bausch Health Ireland Limited
EU
Afiten

Afiten

Amlodipine

Medochemie Ltd.
EU