Europe — EMA
Norit Carbomix (Charcoal, Activated)
GNH USA supplies Norit Carbomix (Activated charcoal), a gastrointestinal adsorbent for acute poisoning, drug overdose and digestive disturbances.
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What is Charcoal, Activated?
Activated charcoal, the active ingredient in Norit Carbomix, is an adsorbent presented as a powdered oral preparation for oral use. It is employed to manage acute poisoning, drug overdose and certain digestive disturbances in patients of all ages as directed by a healthcare professional.
GNH USA supplies Norit Carbomix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Charcoal, Activated used for?
Norit Carbomix, an oral activated charcoal adsorbent, is employed in gastrointestinal decontamination to manage conditions where ingested substances need to be bound and prevented from entering the systemic circulation.
Acute poisoning: reduces systemic absorption of ingested toxins. Drug overdose: binds excess medication to limit toxicity. Digestive disturbances: alleviates gas and bloating by adsorbing intestinal gases.
What are the side effects of Charcoal, Activated?
Common Side Effects: - Constipation: reduced bowel motility may cause hard stools. - Black stools: charcoal imparts a dark colour to feces. - Nausea or vomiting: transient gastrointestinal upset. - Abdominal discomfort: mild cramping or bloating.
Serious or Rare Side Effects: - Aspiration pneumonia: risk if vomitus containing charcoal is inhaled. - Intestinal obstruction: large doses may form a bezoar. - Severe allergic reaction: rare anaphylaxis or urticaria. - Electrolyte imbalance: prolonged use may affect mineral absorption.
What precautions apply to Charcoal, Activated?
Before using Norit Carbomix, consider the following precautions: - Assess airway protection: avoid administration if risk of aspiration exists. - Contraindicated in gastrointestinal perforation or obstruction. - Do not use in patients with compromised motility without medical supervision. - Monitor for signs of severe constipation or bezoar formation. - Store at room temperature: keep in the original pack, protect from moisture.
What does Charcoal, Activated interact with?
Major Interactions (Avoid): - Antacids: alkaline environment reduces charcoal binding capacity. - Oral iron supplements: charcoal adsorbs iron, decreasing absorption. - Life‑saving medications (e.g., digoxin, warfarin): charcoal may prevent their uptake.
Moderate Interactions (Monitor Closely): - Sucralfate: may bind together, reducing efficacy of both agents. - Metformin: charcoal can lower plasma levels, requiring glucose monitoring. - Levothyroxine: adsorption may reduce thyroid hormone absorption, necessitate dose adjustment.



