GNH USA

Europe — EMA

Norfloxacino Pensa

GNH USA supplies Norfloxacino Pensa (Norfloxacin), a fluoroquinolone antibiotic for urinary tract infections, prostatitis, traveler's diarrhea and gonorrhea.

Request sourcing

1
Pack/s

What is Norfloxacin?

Norfloxacin, the active ingredient in Norfloxacino Pensa, is a fluoroquinolone antibiotic presented as an oral dosage form for oral use. It treats bacterial infections such as urinary tract infections, prostatitis, gastrointestinal infections and uncomplicated gonorrhea in adult patients.

GNH USA supplies Norfloxacino Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Norfloxacin used for?

Norfloxacin is a broad‑spectrum fluoroquinolone used to treat infections of the urinary, genitourinary and gastrointestinal tracts.

- Uncomplicated urinary tract infection: eradicates the causative bacteria and resolves urinary symptoms. - Acute prostatitis: eliminates prostate infection and reduces inflammation. - Traveler's diarrhea and other gastrointestinal infections: clears the pathogenic bacteria causing diarrhoea. - Uncomplicated gonorrhea: provides bactericidal activity against Neisseria gonorrhoeae.

What are the side effects of Norfloxacin?

Norfloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhoea: increased bowel movements, sometimes watery. - Headache: transient cranial discomfort. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, swelling, or hives. - Clostridioides difficile infection: severe colitis after antibiotic use. - Peripheral neuropathy: tingling or numbness in extremities.

What precautions apply to Norfloxacin?

Before prescribing Norfloxacino Pensa, clinicians should consider several safety aspects.

- Renal function: adjust therapy in patients with severe renal impairment. - Pregnancy: Category C; use only when benefits outweigh potential fetal risks. - Elderly patients: monitor for tendon injury and central nervous system effects. - Concomitant theophylline or caffeine: anticipate possible increased stimulation. - Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

What does Norfloxacin interact with?

Norfloxacin can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Other fluoroquinolones: additive toxicity and resistance risk. - Warfarin: potentiation of anticoagulant effect, increasing bleeding risk. - Theophylline: elevated serum levels leading to toxicity.

Moderate Interactions (Monitor Closely): - Antacids containing aluminum or magnesium: may decrease norfloxacin absorption; separate dosing by at least 2 hours. - NSAIDs: possible increase in central nervous system adverse effects. - Oral hypoglycemics: may alter blood glucose control, requiring monitoring.

Frequently asked questions

What infections is Norfloxacino Pensa used to treat?+
Norfloxacino Pensa, containing the fluoroquinolone norfloxacin, is indicated for uncomplicated urinary tract infections, acute prostatitis, gastrointestinal infections such as traveler's diarrhea, and uncomplicated gonorrhea in adult patients.
How does norfloxacin work against bacteria?+
Norfloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial DNA from unwinding and re‑winding, leading to cell death and a bactericidal effect.
What is the usual dose of Norfloxacino Pensa?+
The specific dose and treatment duration are determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors.
Is Norfloxacino Pensa safe during pregnancy or breastfeeding?+
Norfloxacino Pensa is classified as Pregnancy Category C. It should be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding is not recommended unless the benefit to the mother outweighs possible infant exposure.
How do I order Norfloxacino Pensa from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Norfloxacino Pensa compare with other fluoroquinolones?+
Norfloxacino Pensa (norfloxacin) shares the class‑wide mechanism of DNA gyrase inhibition but has a slightly narrower spectrum than newer agents like ciprofloxacin or levofloxacin. It is often chosen for specific infections where local resistance patterns favor norfloxacin.
What are the recommended storage conditions for Norfloxacino Pensa?+
Store Norfloxacino Pensa at temperatures below 25 °C, in the original packaging, protected from moisture and direct sunlight to maintain tablet integrity.
How is Norfloxacino Pensa administered?+
Norfloxacino Pensa is taken orally, usually with a full glass of water. The exact timing relative to meals or other medications should follow the prescriber's instructions.
What are the most serious risks associated with Norfloxacino Pensa?+
Serious risks include tendon rupture, especially of the Achilles tendon, QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should seek immediate medical attention if these occur.
Who should not use Norfloxacino Pensa?+
Patients with a known hypersensitivity to norfloxacin or any fluoroquinolone, those with a history of tendon disorders related to fluoroquinolone use, and individuals taking medications that may cause dangerous QT prolongation should avoid Norfloxacino Pensa unless advised otherwise by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Norfloxacin
Route
Oral Use
Manufacturer
Towa Pharmaceutical S.A.
Origin
EU

Related products