Europe — EMA
Norfloxacino Pensa
GNH USA supplies Norfloxacino Pensa (Norfloxacin), a fluoroquinolone antibiotic for urinary tract infections, prostatitis, traveler's diarrhea and gonorrhea.
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What is Norfloxacin?
Norfloxacin, the active ingredient in Norfloxacino Pensa, is a fluoroquinolone antibiotic presented as an oral dosage form for oral use. It treats bacterial infections such as urinary tract infections, prostatitis, gastrointestinal infections and uncomplicated gonorrhea in adult patients.
GNH USA supplies Norfloxacino Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Norfloxacin used for?
Norfloxacin is a broad‑spectrum fluoroquinolone used to treat infections of the urinary, genitourinary and gastrointestinal tracts.
- Uncomplicated urinary tract infection: eradicates the causative bacteria and resolves urinary symptoms. - Acute prostatitis: eliminates prostate infection and reduces inflammation. - Traveler's diarrhea and other gastrointestinal infections: clears the pathogenic bacteria causing diarrhoea. - Uncomplicated gonorrhea: provides bactericidal activity against Neisseria gonorrhoeae.
What are the side effects of Norfloxacin?
Norfloxacin may cause a range of adverse reactions, from mild to severe.
Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhoea: increased bowel movements, sometimes watery. - Headache: transient cranial discomfort. - Rash: mild skin erythema or itching.
Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, swelling, or hives. - Clostridioides difficile infection: severe colitis after antibiotic use. - Peripheral neuropathy: tingling or numbness in extremities.
What precautions apply to Norfloxacin?
Before prescribing Norfloxacino Pensa, clinicians should consider several safety aspects.
- Renal function: adjust therapy in patients with severe renal impairment. - Pregnancy: Category C; use only when benefits outweigh potential fetal risks. - Elderly patients: monitor for tendon injury and central nervous system effects. - Concomitant theophylline or caffeine: anticipate possible increased stimulation. - Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.
What does Norfloxacin interact with?
Norfloxacin can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.
Major Interactions (Avoid): - Other fluoroquinolones: additive toxicity and resistance risk. - Warfarin: potentiation of anticoagulant effect, increasing bleeding risk. - Theophylline: elevated serum levels leading to toxicity.
Moderate Interactions (Monitor Closely): - Antacids containing aluminum or magnesium: may decrease norfloxacin absorption; separate dosing by at least 2 hours. - NSAIDs: possible increase in central nervous system adverse effects. - Oral hypoglycemics: may alter blood glucose control, requiring monitoring.



