Norfloxacino Cinfa

Norfloxacin, the active ingredient in Norfloxacino Cinfa, is a fluoroquinolone presented as an oral tablet for systemic use. It treats bacterial infections of the urinary tract, prostate and gastrointestinal tract in adult patients and targets a broad spectrum of Gram‑negative and some Gram‑positive organisms.

GNH USA supplies Norfloxacino Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU manufacturing standards and providing reliable global distribution.

Norfloxacino Cinfa (norfloxacin) is indicated for infections caused by susceptible bacteria affecting the urinary, prostate and gastrointestinal systems.

- Urinary tract infections: eradicates the causative bacteria, relieving symptoms and preventing recurrence. - Prostatitis: eliminates the infecting organisms, reducing inflammation and improving urinary flow. - Gastrointestinal infections: treats bacterial enteric infections such as traveler's diarrhea, aiding symptom resolution and bacterial clearance.

Adverse reactions may occur with norfloxacin therapy.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon. - QT interval prolongation: may cause cardiac arrhythmias. - Severe allergic reaction: rash, swelling, breathing difficulty requiring immediate medical attention.

Use of norfloxacin requires careful clinical assessment.

- Renal function assessment: adjust dosing in patients with impaired kidney function. - Tendon monitoring: advise patients to report tendon pain or swelling promptly. - Concomitant NSAIDs: avoid combined use due to increased risk of tendon injury. - Elderly patients: use with caution because of higher susceptibility to adverse effects. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Norfloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce norfloxacin absorption. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Theophylline: can raise plasma theophylline concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce contraceptive effectiveness. - Diabetic agents: monitor blood glucose as norfloxacin can affect glycemic control. - Corticosteroids: increased risk of tendon disorders when used together.